A mechanistic approach for islet amyloid polypeptide aggregation to develop anti-amyloidogenic agents for type-2 diabetes
Type-2 diabetes mellitus (DM-2) is a conformational disease involving intrinsically
disordered islet amyloid polypeptide (IAPP), in which a structural transition from …
disordered islet amyloid polypeptide (IAPP), in which a structural transition from …
Effect of pressure on islet amyloid polypeptide aggregation: revealing the polymorphic nature of the fibrillation process
D Radovan, V Smirnovas, R Winter - Biochemistry, 2008 - ACS Publications
Type II diabetes mellitus is a disease which is characterized by peripheral insulin resistance
coupled with a progressive loss of insulin secretion that is associated with a decrease in …
coupled with a progressive loss of insulin secretion that is associated with a decrease in …
Introduction and technical survey: protein aggregation and fibrillogenesis
JR Harris, NGN Milton - … Aggregation and Fibrillogenesis in Cerebral and …, 2012 - Springer
In this chapter we provided the overall background to the subject of protein aggregation and
fibrillogenesis in amyloidogenesis, with introduction and brief discussion of the various …
fibrillogenesis in amyloidogenesis, with introduction and brief discussion of the various …