Conspectus Membrane proteins mediate a plethora of cellular functions and represent
important targets for drug development. Unlike soluble proteins, membrane proteins require …

HAX1 is a relatively small, ubiquitously expressed, predominantly mitochondrial, intrinsically
disordered protein. It has been implicated in the regulation of apoptosis, cell migration …

Although stem/progenitor cell therapy shows potential for myocardial infarction repair,
enhancing the therapeutic efficacy could be achieved through additional genetic …

Functions of intrinsically disordered proteins do not require structure. Such structure-
independent functionality has melted away the classic rigid “lock and key” representation of …

Abstract HCLS1-associated protein X-1 (HAX1) is a multifunctional protein involved in many
cellular processes, including apoptosis, cell migration and calcium homeostasis, but its …

Protein-lipid interactions are an essential element of the function of many membrane ion-
channel proteins. These potential interactions should be considered alongside the diversity …

HAX1 is a human protein with no known homologues or structural domains. Mutations in the
HAX1 gene cause severe congenital neutropenia through mechanisms that are poorly …

Many enteric pathogens employ a type III secretion system (T3SS) to translocate effector
proteins directly into the host cell cytoplasm, where they subvert signalling pathways of the …

Abstract HCLS1-associated protein X-1 (HAX1) is a newly discovered multifunctional cell
regulatory protein that is widely expressed in cells and has a close relationship with multiple …

African swine fever virus (ASFV) infection causes African swine fever (ASF), a virulent
infectious disease that threatens the safety of livestock worldwide. Studies have shown that …