[HTML][HTML] A review of the microbial production of bioactive natural products and biologics
JV Pham, MA Yilma, A Feliz, MT Majid… - Frontiers in …, 2019 - frontiersin.org
A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites,
also known as natural products. Natural products have been a prolific source and an …
also known as natural products. Natural products have been a prolific source and an …
Natural product discovery: past, present, and future
L Katz, RH Baltz - Journal of Industrial Microbiology and …, 2016 - academic.oup.com
Microorganisms have provided abundant sources of natural products which have been
developed as commercial products for human medicine, animal health, and plant crop …
developed as commercial products for human medicine, animal health, and plant crop …
Actinomycetes: still a source of novel antibiotics
O Genilloud - Natural product reports, 2017 - pubs.rsc.org
Covering: 2006 to 2017 Actinomycetes have been, for decades, one of the most important
sources for the discovery of new antibiotics with an important number of drugs and analogs …
sources for the discovery of new antibiotics with an important number of drugs and analogs …
Retrospective analysis of natural products provides insights for future discovery trends
Understanding of the capacity of the natural world to produce secondary metabolites is
important to a broad range of fields, including drug discovery, ecology, biosynthesis, and …
important to a broad range of fields, including drug discovery, ecology, biosynthesis, and …
[HTML][HTML] The evolution of genome mining in microbes–a review
Covering: 2006 to 2016 The computational mining of genomes has become an important
part in the discovery of novel natural products as drug leads. Thousands of bacterial …
part in the discovery of novel natural products as drug leads. Thousands of bacterial …
[HTML][HTML] Natural products as a vital source for the discovery of cancer chemotherapeutic and chemopreventive agents
GM Cragg, JM Pezzuto - Medical Principles and Practice, 2016 - karger.com
Throughout history, natural products have played a dominant role in the treatment of human
ailments. For example, the legendary discovery of penicillin transformed global existence …
ailments. For example, the legendary discovery of penicillin transformed global existence …
High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System
Actinobacteria, particularly those of genus Streptomyces, remain invaluable hosts for the
discovery and engineering of natural products and their cognate biosynthetic pathways …
discovery and engineering of natural products and their cognate biosynthetic pathways …
Metabolomics and genomics in natural products research: complementary tools for targeting new chemical entities
Covering: 2010 to 2021 Organisms in nature have evolved into proficient synthetic chemists,
utilizing specialized enzymatic machinery to biosynthesize an inspiring diversity of …
utilizing specialized enzymatic machinery to biosynthesize an inspiring diversity of …
[HTML][HTML] Cold and hot extremozymes: industrial relevance and current trends
F Sarmiento, R Peralta, JM Blamey - Frontiers in bioengineering and …, 2015 - frontiersin.org
The development of enzymes for industrial applications relies heavily on the use of
microorganisms. The intrinsic properties of microbial enzymes, eg, consistency …
microorganisms. The intrinsic properties of microbial enzymes, eg, consistency …
Strategies to diversify natural products for drug discovery
G Li, HX Lou - Medicinal research reviews, 2018 - Wiley Online Library
Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …
microorganisms that play a pivotal role in drug discovery due to their immense structural …