A Markovian dynamics for Caenorhabditis elegans behavior across scales
How do we capture the breadth of behavior in animal movement, from rapid body twitches to
aging? Using high-resolution videos of the nematode worm Caenorhabditis elegans, we …
aging? Using high-resolution videos of the nematode worm Caenorhabditis elegans, we …
Ergodic characterization of nonergodic anomalous diffusion processes
Anomalous diffusion in various complex systems abounds in nature and spans multiple
space and time scales. Canonical characterization techniques that rely upon mean squared …
space and time scales. Canonical characterization techniques that rely upon mean squared …
High-throughput behavioral screen in C. elegans reveals Parkinson's disease drug candidates
We recently linked branched-chain amino acid transferase 1 (BCAT1) dysfunction with the
movement disorder Parkinson's disease (PD), and found that RNAi-mediated knockdown of …
movement disorder Parkinson's disease (PD), and found that RNAi-mediated knockdown of …
Multifractal auditory stimulation promotes the effect of multifractal torso sway on spatial perception: Evidence from distance perception by blindwalking
D Kelty-Stephen, OD Similton, E Rabinowitz… - Ecological …, 2023 - Taylor & Francis
Stimulation and movement interact non-linearly across multiple scales—a point empirically
and quantitatively available through multifractal structure. Multifractal movements might …
and quantitatively available through multifractal structure. Multifractal movements might …
Ce Lab, a microfluidic platform for the study of life history traits, reveals metformin and SGK-1 regulation of longevity and reproductive span
The potential to carry out high-throughput assays in a whole organism in a small space is
one of the benefits of C. elegans, but worm assays often require a large sample size with …
one of the benefits of C. elegans, but worm assays often require a large sample size with …
Potential of multifractal analysis for characterizing movements of biological objects
NV Zaitseva, MA Zemlyanova, AM Ignatova… - Biology Bulletin …, 2023 - Springer
The object of study is data (time series) on movements of laboratory animals (rats in the
“open field” maze), which reflect the dynamics of changes in speed and position of objects in …
“open field” maze), which reflect the dynamics of changes in speed and position of objects in …
Multifractal spectral features enhance classification of anomalous diffusion
Anomalous diffusion processes, characterized by their nonstandard scaling of the mean-
squared displacement, pose a unique challenge in classification and characterization. In a …
squared displacement, pose a unique challenge in classification and characterization. In a …
Maximally predictive ensemble dynamics from data
We leverage the interplay between microscopic variability and macroscopic order to connect
physical descriptions across scales directly from data, without underlying equations. We …
physical descriptions across scales directly from data, without underlying equations. We …
Insulin signaling shapes fractal scaling of C. elegans behavior
Fractal scaling in animal behavioral activity, where similar temporal patterns appear
repeatedly over a series of magnifications among time scales, governs the complex …
repeatedly over a series of magnifications among time scales, governs the complex …
Fractal scaling of C. elegans behavior is shaped by insulin signaling
Fractal scaling governs the complex behavior of various animal species and, in humans, can
be altered by neurodegenerative diseases and aging. However, the mechanism underlying …
be altered by neurodegenerative diseases and aging. However, the mechanism underlying …