Triple-negative breast cancer (TNBC) is the most complex, aggressive and fatal subtype of
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …

The RASSF1A tumour suppressor is a scaffold protein that is involved in cell signalling.
Increasing evidence shows that this protein sits at the crossroad of a complex signalling …

Triple-negative breast cancer (TNBC) is an aggressive breast tumor subtype that currently
lacks targeted treatment options. The role played by the insulin-like growth factor-1 (IGF-1) …

Background Cell migration and invasion are essential processes for metastatic
dissemination of cancer cells. Significant progress has been made in developing new …

Glioblastoma (GBMs) is the most common and aggressive type of primary brain tumor in
adults with dismal prognosis despite radical surgical resection coupled with chemo-and …

Simple Summary In 2020, the global cancer database GLOBOCAN estimated 19.3 million
new cancer cases worldwide. The discovery of targeted therapies may help prognosis and …

Simple Summary In the current era of precision medicine, the management of patients with
brain metastases (BMs) is rapidly evolving. The technical evolution of radiotherapy, now …

Abstract The Hippo pathway effectors Yes-associated protein 1 (YAP) and its homolog TAZ
are transcriptional coactivators that control gene expression by binding to TEA domain …

Purpose Danger signals released by ionizing radiation (IR) can theoretically stimulate
immune activation in the tumor environment (TME), but IR alone is not sufficient to induce an …

Abstract MicroRNA (miR)‑497 has been reported as a tumor suppressor in various cancer
types. Nonetheless, the regulation of triple‑negative breast cancer (TNBC) by miR‑497 …