The brain is a heterogeneous organ with regionally varied and constantly changing
energetic needs. Blood vessels in the brain are equipped with control mechanisms that …

From a structural perspective, the predominant glial cell of the central nervous system, the
astrocyte, is positioned to regulate synaptic transmission and neurovascular coupling: the …

The cellular mechanisms underlying functional hyperemia—the coupling of neuronal
activation to cerebral blood vessel responses—are not yet known. Here we show in rat …

The role of interneurons in neurovascular coupling was investigated by patch-clamp
recordings in acute rat cortical slices, followed by single-cell reverse transcriptase-multiplex …

✓ Recently, the authors showed that thrombin contributes to the formation of brain edema
following intracerebral hemorrhage. The current study examines whether the action of …

Functional variations in cerebral cortical activity are accompanied by local changes in blood
flow, but the mechanisms underlying this physiological coupling are not well understood …

The tight coupling between increased neuronal activity and local cerebral blood flow, known
as functional hyperemia, is essential for normal brain function. However, its cellular and …

Increases in cortical cerebral blood flow are induced by stimulation of basal forebrain
cholinergic neurons. This response is mediated in part by nitric oxide (NO) and reportedly …

Electroacupuncture (EA) is a novel therapy based on traditional acupuncture combined with
modern eletrotherapy that is currently being investigated as a treatment for acute ischemic …

The role of GABA in regulating cerebral microvessels was examined in the parenchyma of
the hippocampus and the surface of the neocortex. Microvessels were monitored in in vitro …