Group B streptococcus (GBS) infection remains a leading cause of sepsis, pneumonia, and
meningitis in infants. Rates of GBS early onset disease have declined following the …

Vaccines work primarily by eliciting antibodies, even when recovery from natural infection
depends on cellular immunity. Large efforts have therefore been made to identify microbial …

Staphylococcus aureus and Staphylococcus epidermidis are frequently associated with
medical device infections that involve establishment of a bacterial biofilm on the device …

Changes at the cell surface enable bacteria to survive in dynamic environments, such as
diverse niches of the human host. Here, we reveal “Periscope Proteins” as a widespread …

Invasive infections by group B streptococci (iGBS) are the leading cause of sepsis and
meningitis in the first three months of life worldwide. The clinical and microbiological …

Multidrug-resistant (MDR) Enterococcus faecalis are major causes of hospital-acquired
infections. Numerous clinical strains of E. faecalis harbor a large pathogenicity island that …

Biological systems consist of multiple components of different physical and chemical
properties that require complex and dynamic regulatory loops to function efficiently. The …

The botulinum neurotoxin-like toxin from Weissella oryzae (BoNT/Wo) is one of the BoNT-
like toxins recently identified outside of the Clostridium genus. We show that, like the …

Cell wall-anchored LPxTG proteins derived from the Lactobacillus are recognized to have
excellent adhesion and gastrointestinal tolerance functions. Since the motif of LPxTG can …

Bacteria sense, interact with, and modify their environmental niche by deploying a molecular
ensemble at the cell surface. The changeability of this exposed interface, combined with …