Animals, anxiety, and anxiety disorders: How to measure anxiety in rodents and why

J Harro - Behavioural brain research, 2018 - Elsevier
Measurement of anxiety is desirable for the benefit of drug development and understanding
the brain function and mental well-being. Animal models offer the advantages of detailed …

Animal models of depression: pros and cons

J Harro - Cell and tissue research, 2019 - Springer
Animal models of depression are certainly needed but the question in the title has been
raised owing to the controversies in the interpretation of the readout in a number of tests, to …

Oxidative metabolism alterations in the emotional brain of anxiety-prone rats

CR McCoy, MN Sabbagh, JP Huaman… - Progress in Neuro …, 2019 - Elsevier
Mood disorders such as anxiety and depression are heterogeneous disorders with many
sufferers unresponsive to current pharmacological treatments. Individual differences in …

Autistic-like behaviour and changes in thalamic cell numbers a rat model of valproic acid-induced autism; A behavioural and stereological study

E Horata, H Ay, D Aslan - Brain Research, 2024 - Elsevier
The contribution of the thalamus to the development and behavioural changes in autism
spectrum disorders (ASD), a neurodevelopmental syndrome, remains unclear. The aim of …

Cerebral oxidative metabolism mapping in four genetic mouse models of anxiety and mood disorders

D Matrov, T Kaart, L Lanfumey, R Maldonado… - Behavioural brain …, 2019 - Elsevier
The psychopathology of depression is highly complex and the outcome of studies on animal
models is divergent. In order to find brain regions that could be metabolically distinctively …

Comprehensive mapping of cytochrome c oxidase activity in the rat brain after sub-chronic ketamine administration

D Matrov, S Imbeault, M Kanarik, M Shkolnaya… - Acta …, 2020 - Elsevier
Ketamine is a noncompetitive antagonist of glutamatergic N-methyl-d-aspartate receptors. Its
acute effects on healthy volunteers and schizophrenia patients mimic some acute psychotic …

Avaliação do efeito da risperidona e do aripiprazol sobre o comportamento tipo-autista e parâmetros oxidativos em ratos jovens: estudo pré-clinico

CLM Medeiros - 2019 - bdtd.ibict.br
Autistic Spectrum Disorder is a neurodevelopmental disorder with varying degrees of
impairment in individuals. Social comununication deficits and the presence of restricted and …

Modelos animais para estudos de transtornos psiquiátricos: uma revisão bibliográfica

JB Martins - 2019 - repositorio.ufu.br
Os modelos animais para transtornos psiquiátricos envolvem estudos para a esquizofrenia,
a depressão, a ansiedade, os transtornos do espectro autista, entre outros, que afetam uma …