Analytical methodologies for the determination of benzodiazepines in biological samples

K Persona, K Madej, P Knihnicki… - Journal of Pharmaceutical …, 2015 - Elsevier
Benzodiazepine drugs belong to important and most widely used medicaments. They
demonstrate such therapeutic properties as anxiolytic, sedative, somnifacient …

Analytical methods for determination of benzodiazepines. A short review

P Szatkowska, M Koba, P Kośliński, J Wandas… - Open …, 2014 - degruyter.com
Benzodiazepines (BDZs) are generally commonly used as anxiolytic and/or hypnotic drugs
as a ligand of the GABAA-benzodiazepine receptor. Moreover, some of benzodiazepines …

A novel electrochemical nanocomposite imprinted sensor for the determination of lorazepam based on modified polypyrrole@ sol-gel@ gold nanoparticles/pencil …

B Rezaei, MK Boroujeni, AA Ensafi - Electrochimica Acta, 2014 - Elsevier
A new sensitive and selective imprinted electrochemical sensor was developed for
lorazepam determination, which is based on a pencil graphite electrode (PGE) modified with …

A rapid ultrasound-assisted dispersive liquid–liquid microextraction followed by ultra-performance liquid chromatography for the simultaneous determination of seven …

P Fernández, C González, MT Pena, AM Carro… - Analytica Chimica …, 2013 - Elsevier
A simple and efficient ultrasound-assisted dispersive liquid–liquid microextraction (UA-
DLLME) method has been developed for the determination of seven benzodiazepines …

Simplifying sample preparation using fabric phase sorptive extraction technique for the determination of benzodiazepines in blood serum by high‐performance liquid …

V Samanidou, I Kaltzi, A Kabir… - Biomedical …, 2016 - Wiley Online Library
Fabric phase sorptive extraction (FPSE), a recently introduced novel sample preparation
technology, has been evaluated for the extraction of benzodiazepines from human blood …

[HTML][HTML] QuEChERS extraction of benzodiazepines in biological matrices

JL Westland, FL Dorman - Journal of pharmaceutical analysis, 2013 - Elsevier
Two common analytical chemical problems often encountered when using chromatographic
techniques in drug analysis are matrix interferences and ion suppression. Common sample …

High throughput bar adsorptive microextraction: A novel cost-effective tool for monitoring benzodiazepines in large number of biological samples

SM Ahmad, JMF Nogueira - Talanta, 2019 - Elsevier
In this work, we propose an innovative high throughput (HT) apparatus using the bar
adsorptive microextraction (BAμE) technique, which enables the simultaneous enrichment of …

Mixed‐mode SPE for a multi‐residue analysis of benzodiazepines in whole blood using rapid GC with negative‐ion chemical ionization MS

N Karlonas, A Padarauskas… - Journal of separation …, 2013 - Wiley Online Library
A sensitive and selective method for simultaneous quantitation of 15 benzodiazepines in
human whole blood using rapid GC with negative‐ion chemical ionization MS is proposed …

Application of bar adsorptive microextraction for the determination of levels of tricyclic antidepressants in urine samples

MN Oliveira, OC Gonçalves, SM Ahmad, JK Schneider… - Molecules, 2021 - mdpi.com
This work entailed the development, optimization, validation, and application of a novel
analytical approach, using the bar adsorptive microextraction technique (BAμE), for the …

Voltammetric electronic tongue for the simultaneous determination of three benzodiazepines

A Herrera-Chacón, F Torabi, F Faridbod, JB Ghasemi… - Sensors, 2019 - mdpi.com
The presented manuscript reports the simultaneous detection of a ternary mixture of the
benzodiazepines diazepam, lorazepam, and flunitrazepam using an array of voltammetric …