Cytokinesis is a temporally and spatially regulated process through which the cellular
constituents of the mother cell are partitioned into two daughter cells, permitting an increase …

Centrosomes, spindle pole bodies, and related structures in other organisms are a
morphologically diverse group of organelles that share a common ability to nucleate and …

How the actin cytoskeleton assembles into different structures to drive diverse cellular
processes is a fundamental cell biological question. In addition to orchestrating the …

The septation initiation network (SIN) regulates aspects of cell growth and division in
Schizosaccharomyces pombe and is essential for cytokinesis. Insufficient signalling results …

In both animal cells and fungi, cytokinesis proceeds via a contractile actomyosin ring (CAR).
Many CAR components and regulators are evolutionarily conserved. In …

The Ase1/Prc1 proteins constitute a conserved microtubule-associated protein family that is
implicated in central spindle formation and cytokinesis. Here we characterize a role for …

Cdc14 phosphatases antagonize cyclin-dependent kinase–directed phosphorylation events
and are involved in several facets of cell cycle control. We investigate the role of the fission …

In many eukaryotes, cytokinesis requires the assembly and constriction of an actomyosin-
based contractile ring. Despite the central role of this ring in cytokinesis, the mechanism of F …

The fission yeast septation initiation network, or SIN, is a signal transduction network that is
required for septum formation in Schizosaccharomyces pombe. Its activity is tightly regulated …

The septation initiation network (SIN) triggers the onset of cytokinesis in the fission yeast
Schizosaccharomyces pombe by promoting contraction of the medially placed F-actin ring …