Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors

R Figueira, DW Holden - Microbiology, 2012 - microbiologyresearch.org
Salmonella enterica serovars cause severe disease in humans, such as gastroenteritis and
typhoid fever. The bacteria are able to invade and replicate within host cells, including …

F4/80 as a major macrophage marker: the case of the peritoneum and spleen

A dos Anjos Cassado - Macrophages: Origin, functions and …, 2017 - Springer
Tissue macrophages are a heterogeneous cell population residing in all body tissues that
contribute to the maintenance of homeostasis and trigger immune activation in response to …

Internalization of Salmonella by Macrophages Induces Formation of Nonreplicating Persisters

S Helaine, AM Cheverton, KG Watson, LM Faure… - Science, 2014 - science.org
Many bacterial pathogens cause persistent infections despite repeated antibiotic exposure.
Bacterial persisters are antibiotic-tolerant cells, but little is known about their growth status …

Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium

N Robinson, S McComb, R Mulligan, R Dudani… - Nature …, 2012 - nature.com
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a virulent pathogen that
induces rapid host death. Here we observed that host survival after infection with S …

Persistent bacterial infections: the interface of the pathogen and the host immune system

DM Monack, A Mueller, S Falkow - Nature Reviews Microbiology, 2004 - nature.com
Persistent bacterial infections involving Mycobacterium tuberculosis, Salmonella enterica
serovar Typhi (S. typhi) and Helicobacter pylori pose significant public-health problems …

Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole

CL Birmingham, AC Smith, MA Bakowski… - Journal of Biological …, 2006 - ASBMB
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative intracellular
pathogen that causes disease in a variety of hosts. S. Typhimurium actively invade host cells …

Salmonella – the ultimate insider. Salmonella virulence factors that modulate intracellular survival

JA Ibarra, O Steele‐Mortimer - Cellular microbiology, 2009 - Wiley Online Library
Salmonella enterica serovar Typhimurium is a common facultative intracellular pathogen
that causes food‐borne gastroenteritis in millions of people worldwide. Intracellular survival …

Salmonella typhimurium Persists within Macrophages in the Mesenteric Lymph Nodes of Chronically Infected Nramp1+/+ Mice and Can Be Reactivated by IFNγ …

DM Monack, DM Bouley, S Falkow - The Journal of experimental …, 2004 - rupress.org
Host-adapted strains of Salmonella are capable of establishing a persistent infection in their
host often in the absence of clinical disease. The mouse model of Salmonella infection has …

Bacterial manipulation of innate immunity to promote infection

L Diacovich, JP Gorvel - Nature Reviews Microbiology, 2010 - nature.com
The mammalian innate immune response provides a barrier against invading pathogens.
Innate immune mechanisms are used by the host to respond to a range of bacterial …

Splenic macrophage subsets and their function during blood-borne infections

H Borges da Silva, R Fonseca, RM Pereira… - Frontiers in …, 2015 - frontiersin.org
The spleen is one of the major immunological sites for maintaining blood homeostasis.
Previous studies showed that heterogeneous splenic macrophage populations contribute in …