[HTML][HTML] Crosstalk between mitochondrial biogenesis and mitophagy to maintain mitochondrial homeostasis
L Liu, Y Li, G Chen, Q Chen - Journal of Biomedical Science, 2023 - Springer
Mitochondrial mass and quality are tightly regulated by two essential and opposing
mechanisms, mitochondrial biogenesis (mitobiogenesis) and mitophagy, in response to …
mechanisms, mitochondrial biogenesis (mitobiogenesis) and mitophagy, in response to …
[HTML][HTML] Delineating the role of nuclear receptors in colorectal cancer, a focused review
Colorectal cancer (CRC) stands as one of the most prevalent form of cancer globally,
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …
causing a significant number of deaths, surpassing 0.9 million in the year 2020. According to …
[HTML][HTML] Lipid reprogramming induced by the TFEB-ERRα axis enhanced membrane fluidity to promote EC progression
X Mao, H Lei, T Yi, P Su, S Tang, Y Tong… - Journal of Experimental …, 2022 - Springer
Background Estrogen-related receptor α (ERRα) has been reported to play a critical role in
endometrial cancer (EC) progression. However, the underlying mechanism of ERRα …
endometrial cancer (EC) progression. However, the underlying mechanism of ERRα …
[HTML][HTML] Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression
Q Wen, X Xie, C Chen, B Wen, Y Liu, J Zhou… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Elucidating the mechanism for the high metastasis capacity of Endometrial cancer (EC) is
crucial to improve treatment outcomes of EC. We have recently reported that nicotinamide N …
crucial to improve treatment outcomes of EC. We have recently reported that nicotinamide N …
[HTML][HTML] Gemcitabine and XCT790, an ERRα inverse agonist, display a synergistic anticancer effect in pancreatic cancer
S Liu, H Liang, Z Yang, C Cai, Z Wu, X Wu… - … journal of medical …, 2022 - ncbi.nlm.nih.gov
Pancreatic cancer (PC) is one of the most fatal and chemoresistant malignancies with a poor
prognosis. The current therapeutic options for PC have not achieved satisfactory results due …
prognosis. The current therapeutic options for PC have not achieved satisfactory results due …
[HTML][HTML] Transcription factor movement and exercise-induced mitochondrial biogenesis in human skeletal muscle: Current knowledge and future perspectives
DF Taylor, DJ Bishop - International Journal of Molecular Sciences, 2022 - mdpi.com
In response to exercise, the oxidative capacity of mitochondria within skeletal muscle
increases through the coordinated expression of mitochondrial proteins in a process termed …
increases through the coordinated expression of mitochondrial proteins in a process termed …
Estrogen-related receptor alpha in select host functions and cancer: new frontiers
HS Ranhotra - Molecular and Cellular Biochemistry, 2022 - Springer
Eukaryotic gene expression is under the tight control of transcription factors, which includes
the estrogen-related receptor alpha (ERRα). The endogenous ligand (s) acting as ERRα …
the estrogen-related receptor alpha (ERRα). The endogenous ligand (s) acting as ERRα …
From physiology to pathology: the role of mitochondria in acute kidney injuries and chronic kidney diseases
L Zhang, M Miao, X Xu, M Bai, M Wu, A Zhang - Kidney Diseases, 2023 - karger.com
Background: Renal diseases remain an increasing public health issue affecting millions of
people. The kidney is a highly energetic organ that is rich in mitochondria. Numerous …
people. The kidney is a highly energetic organ that is rich in mitochondria. Numerous …
Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates
AM Riojas, KD Reeves, RE Shade… - Physiological …, 2022 - journals.physiology.org
Blood pressure (BP) is influenced by genetic variation and sodium intake with sex-specific
differences; however, studies to identify renal molecular mechanisms underlying the …
differences; however, studies to identify renal molecular mechanisms underlying the …
[HTML][HTML] ERRα Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis
S Tang, J Ma, P Su, H Lei, Y Tong, L Cai, S Xu… - International Journal of …, 2023 - mdpi.com
Estrogen-related receptor alpha (ERRα) plays an important role in endometrial cancer (EC)
progression. However, the biological roles of ERRα in EC invasion and metastasis are not …
progression. However, the biological roles of ERRα in EC invasion and metastasis are not …