Recent advances and clinical potential of near infrared photothermal conversion materials for photothermal hepatocellular carcinoma therapy

RL Ge, PN Yan, Y Liu, ZS Li… - Advanced Functional …, 2023 - Wiley Online Library
Growing concern about photothermal tumor therapy (PTT) as a promising alternative to
conventional liver cancer treatment, which is a treatment strategy that utilizes near‐infrared …

Biomaterials Facilitating Dendritic Cell‐Mediated Cancer Immunotherapy

H Dong, Q Li, Y Zhang, M Ding, Z Teng… - Advanced …, 2023 - Wiley Online Library
Dendritic cell (DC)‐based cancer immunotherapy has exhibited remarkable clinical
prospects because DCs play a central role in initiating and regulating adaptive immune …

Programmed Targeting Pyruvate Metabolism Therapy Amplified Single‐Atom Nanozyme‐Activated Pyroptosis for Immunotherapy

R Niu, Y Liu, B Xu, R Deng, S Zhou, Y Cao… - Advanced …, 2024 - Wiley Online Library
Increasing cellular immunogenicity and reshaping the immune tumor microenvironment
(TME) are crucial for antitumor immunotherapy. Herein, this work develops a novel single …

Sulfation at Glycopolymer Side Chains Switches Activity at the Macrophage Mannose Receptor (CD206) In Vitro and In Vivo

F Mastrotto, M Pirazzini, S Negro… - Journal of the …, 2022 - ACS Publications
The mannose receptor (CD206) is an endocytic receptor expressed by selected innate
immune cells and nonvascular endothelium, which plays a critical role in both homeostasis …

Engineering hydrophilic/hydrophobic moieties of ratiometric fluorescence probe to visualize whole cytoplasmic polarity

Y Liu, S Zhou, W Jin, J Niu, KN Wang, Z Liu… - Chemical Engineering …, 2023 - Elsevier
Intracellular polarity is an essential parameter to indicate the property of microenvironment
in the whole cell. The polarity is closely related to various physiological processes in …

Self-shrinking supramolecular nanoparticles syndicate energy suppression and NIR-II mild photothermal amplification of mitochondrial oxidative stress for breast …

H Liu, J Xu, M Ye, H Zhang, L Han, J Wang, P Xue… - Nano Research, 2024 - Springer
Photothermal therapy (PTT) may lead to healthy tissue damage, tumor metastasis, and
recurrence, which makes mild photothermal therapy (mild PTT) stand out. However …

Identification of a Self-Assembling Small-Molecule Cancer Vaccine Adjuvant with an Improved Toxicity Profile

SH Zhuo, N Noda, K Hioki, S Jin… - Journal of Medicinal …, 2023 - ACS Publications
Protein or peptide cancer vaccines usually include immune potentiators, so-called
adjuvants. However, it remains challenging to identify structurally simple, chemically …

Cyclic dinucleotide self-assembled nanoparticles as a carrier-free delivery platform for STING-mediated cancer immunotherapy

L Zhao, SH Zhuo, TY Wang, JJ Wu, JY Su… - CCS …, 2024 - chinesechemsoc.org
Cyclic dinucleotides (CDNs) are natural agonists of the stimulator of interferon genes
(STING), which is an attractive immunotherapy target. Currently, CDNs and their derivatives …

Nanogalvanic Cells Release Highly Reactive Electrons in Tumors to Effectively Eliminate Tumors

WQ Huang, YQ Zhu, F Gao, W You, G Chen… - Advanced …, 2024 - Wiley Online Library
External stimuli triggering chemical reactions in cancer cells to generate highly reactive
chemical species are very appealing for cancer therapy, in which external irradiation …

Nitrogen vacancy-rich carbon nitride anchored with iron atoms for efficient redox dyshomeostasis under ultrasound actuation

M He, X Wang, H Yu, Y Zhao, L Zhang, Z Xu, Y Kang… - Biomaterials, 2024 - Elsevier
Abstract Traditional Fe-based Fenton reaction for inducing oxidative stress is restricted by
random charge transfer without oriental delivery, and the resultant generation of reactive …