The NLRP3 inflammasome is cytosolic multi-protein complex that induces inflammation and
pyroptotic cell death in response to both pathogen (PAMPs) and endogenous activators …

Lipopolysaccharide (LPS) is the main structural component of the outer membrane of most
Gram-negative bacteria and has diverse immunostimulatory and procoagulant effects. Even …

Microglia maintain brain homeostasis by removing neuron-derived components such as
myelin and cell debris. The evidence linking microglia to neurodegenerative diseases is …

Graphene-and graphene oxide-based nanomaterials have gained broad interests in
research because of their unique physiochemical properties. The 2D allotropic structure …

Autophagy, a conserved catabolic process, plays an immensely significant role in a variety
of diseases. However, whether it imparts a protective function in diseases remains …

Autophagy is well equipped functionally to isolate microbial pathogens in autophagosomes
and to carry out their clearance by dismemberment in the course of catabolic processes in …

Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of
core genes, including the family of autophagy-related genes (ATG). Autophagy is a “double …

Autophagy has broad functions in immunity, ranging from cell-autonomous defence to
coordination of complex multicellular immune responses. The successful resolution of …

Autophagy is a fundamental eukaryotic pathway that has multiple effects on immunity.
Autophagy is induced by pattern recognition receptors and, through autophagic adaptors, it …

The cellular degradative pathway of autophagy has a fundamental role in immunity. Here,
we review the function of autophagy and autophagy proteins in inflammation. We discuss …