Cancer is the leading cause of death in dogs, in part because many cases are identified at
an advanced stage when clinical signs have developed, and prognosis is poor. Increased …

Cancer is the leading cause of death in dogs, yet there are no established screening
paradigms for early detection. Liquid biopsy methods that interrogate cancer-derived …

Simple Summary Genetic molecular testing is starting to become part of standard clinical
practice for dogs with cancer as it can assist veterinarians with diagnosis, provide …

Melanoma of the dog and cat poses a clinical challenge to veterinary practitioners across
the globe. As knowledge evolves, so too do clinical practices. However, there remain …

The human cancer precision medicine paradigm has been built on the foundation of
understanding cancer's genomic underpinnings and great individual variability Remarkable …

This proof-of-concept study demonstrates that blood-based liquid biopsy using next
generation sequencing of cell-free DNA can non-invasively detect multiple classes of …

Liquid biopsy (LB) is a concept that is rapidly gaining ground in the biomedical field. Its
concept is largely based on the detection of circulating cell-free DNA (ccfDNA) fragments …

Domestic dogs (Canis lupus familiaris) serve as valuable translational models for human
cancer research due to their biological similarities. Canine mammary tumors (CMTs) …

Circulating tumor DNA (ctDNA) sequencing holds considerable promise for early diagnosis
and detection of surveillance and minimal residual disease. Blood ctDNA monitors specific …

Canine oral melanoma (COM) is a highly aggressive tumour associated with poor prognosis
due to metastasis and resistance to conventional anti-cancer therapies. As with human …