Background Potential therapeutic targets and clinical trials for Huntingtonʼs disease have
grown immensely in the last decade. However, to improve clinical trial outcomes, there is a …

This paper investigated cortical folding in Huntington's disease to understand how disease
progression impacts the surface of the cortex. Cortical morphometry changes in eight gyral …

Premanifest Huntington's disease (pre-HD) individuals typically show increased task-related
functional magnetic resonance imaging (fMRI), suggested to reflect compensatory …

Exposure to psychosocial adversity (PA) is associated with poor behavioral, physical, and
mental health outcomes in adulthood. Growing evidence suggests that deficits in executive …

As Huntington's disease (HD) progresses, motor and cognitive impairments worsen, making
it difficult to hold, shift, and divide attention between multiple tasks. Although previous …

CAG repeat expansion on chromosome 4. The primary symptoms of disease include
progressively worsening chorea, or involuntary dance-like symptoms, accompanied by …