[HTML][HTML] Investigative genetic genealogy: Current methods, knowledge and practice
Investigative genetic genealogy (IGG) has emerged as a new, rapidly growing field of
forensic science. We describe the process whereby dense SNP data, commonly comprising …
forensic science. We describe the process whereby dense SNP data, commonly comprising …
Probabilistic genotyping software: an overview
The interpretation of mixed profiles from DNA evidentiary material is one of the more
challenging duties of the forensic scientist. Traditionally, analysts have used a “binary” …
challenging duties of the forensic scientist. Traditionally, analysts have used a “binary” …
A Review of Probabilistic Genotyping Systems: EuroForMix, DNAStatistX and STRmix™
Probabilistic genotyping has become widespread. EuroForMix and DNAStatistX are both
based upon maximum likelihood estimation using a γ model, whereas STRmix™ is a …
based upon maximum likelihood estimation using a γ model, whereas STRmix™ is a …
Forensic molecular biomarkers for mixture analysis
F Oldoni, D Podini - Forensic Science International: Genetics, 2019 - Elsevier
The deconvolution of DNA mixtures has gathered the attention of forensic DNA scientists for
over two decades. To enhance mixture deconvolution capabilities, a new generation of …
over two decades. To enhance mixture deconvolution capabilities, a new generation of …
Examining performance and likelihood ratios for two likelihood ratio systems using the PROVEDIt dataset
S Riman, H Iyer, PM Vallone - PLoS One, 2021 - journals.plos.org
A likelihood ratio (LR) system is defined as the entire pipeline of the measurement and
interpretation processes where probabilistic genotyping software (PGS) is a piece of the …
interpretation processes where probabilistic genotyping software (PGS) is a piece of the …
Single-cell transcriptome sequencing allows genetic separation, characterization and identification of individuals in multi-person biological mixtures
L Kulhankova, D Montiel González, E Bindels… - Communications …, 2023 - nature.com
Identifying individuals from biological mixtures to which they contributed is highly relevant in
crime scene investigation and various biomedical research fields, but despite previous …
crime scene investigation and various biomedical research fields, but despite previous …
Forensic DNA analysis
BR McCord, Q Gauthier, S Cho, MN Roig… - Analytical …, 2018 - ACS Publications
This Review focuses on recent developments in forensic DNA typing. It highlights important
recent advances and issues in forensic human identification and identifies representative …
recent advances and issues in forensic human identification and identifies representative …
A comparison of likelihood ratios obtained from EuroForMix and STRmix™
Likelihood ratios (LR) differences between the probabilistic genotyping software EuroForMix
and STRmix™ are examined. After considering differences in the allele probabilities, the …
and STRmix™ are examined. After considering differences in the allele probabilities, the …
Uncertainty in probabilistic genotyping of low template DNA: A case study comparing STRMix™ and TrueAllele™
WC Thompson - Journal of Forensic Sciences, 2023 - Wiley Online Library
Two probabilistic genotyping (PG) programs, STRMix™ and TrueAllele™, were used to
assess the strength of the same item of DNA evidence in a federal criminal case, with …
assess the strength of the same item of DNA evidence in a federal criminal case, with …
A tale of two PG systems: A comparison of the two most widely used continuous probabilistic genotyping systems in the United States
SA Greenspoon, L Schiermeier‐Wood… - Journal of Forensic …, 2024 - Wiley Online Library
The development of probabilistic genotyping (PG) systems to quantitatively analyze DNA
mixture samples has been transformative in forensic science. TrueAllele® Casework (TA) …
mixture samples has been transformative in forensic science. TrueAllele® Casework (TA) …