Armadillo (ARM)-repeat proteins form a large family with diverse and fundamental functions
in many eukaryotes. ARM-repeat proteins have largely been characterised in multicellular …

Cytokinesis is the final event of the cell division cycle, and its completion results in
irreversible partition of a mother cell into two daughter cells. Cytokinesis was one of the first …

Several members of the tumour-necrosis/nerve-growth factor (TNF/NGF) receptor family
activate the transcription factor NF-KB through a common adaptor protein, Traf2 (refs 1–5) …

We have identified a Schizosaccharomyces pombe gene with homology to the budding
yeast gene CDC5, the Drosophila gene polo, and the mammalian family of genes encoding …

Schizosaccharomyces pombe is an excellent organism in which to study cytokinesis as it
divides by medial fission using an F-actin contractile ring. To enhance our understanding of …

Centrosomes, spindle pole bodies, and related structures in other organisms are a
morphologically diverse group of organelles that share a common ability to nucleate and …

The S. pombe cdc15 gene is essential for cell division. cdc15 ts mutants do not form a
septum, but growth and nuclear division continue, leading to formation of multinucleate cells …

Little is known about the mechanisms that establish the position of the division plane in
eukaryotic cells. Wild-type fission yeast cells divide by forming a septum in the middle of the …

The spg1 gene (septum-promoting GTPase) was cloned as a multicopy suppressor of a
dominant-negative mutant of the Cdc7p kinase. It encodes a small GTPase of the Ras …

Proper completion of mitosis requires careful coordination of numerous cellular events. It is
crucial, for example, that cells do not initiate spindle disassembly and cytokinesis until …