Circadian rhythm as a therapeutic target
The circadian clock evolved in diverse organisms to integrate external environmental
changes and internal physiology. The clock endows the host with temporal precision and …
changes and internal physiology. The clock endows the host with temporal precision and …
Circadian clocks and insulin resistance
DJ Stenvers, FAJL Scheer, P Schrauwen… - Nature Reviews …, 2019 - nature.com
Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …
major cause of morbidity and mortality. The circadian timing system consists of a central …
[HTML][HTML] Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity
N Vujović, MJ Piron, J Qian, SL Chellappa… - Cell metabolism, 2022 - cell.com
Late eating has been linked to obesity risk. It is unclear whether this is caused by changes in
hunger and appetite, energy expenditure, or both, and whether molecular pathways in …
hunger and appetite, energy expenditure, or both, and whether molecular pathways in …
[HTML][HTML] Timing of daily calorie loading affects appetite and hunger responses without changes in energy metabolism in healthy subjects with obesity
LC Ruddick-Collins, PJ Morgan, CL Fyfe, JAN Filipe… - Cell metabolism, 2022 - cell.com
Morning loaded calorie intake in humans has been advocated as a dietary strategy to
improve weight loss. This is also supported by animal studies suggesting time of eating can …
improve weight loss. This is also supported by animal studies suggesting time of eating can …
[HTML][HTML] Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism
OH Meléndez-Fernández, JA Liu… - International Journal of …, 2023 - mdpi.com
Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …
allowing 24-hour healthcare, commerce and production, and expanding social life around …
Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption
Y Touitou, A Reinberg, D Touitou - Life sciences, 2017 - Elsevier
Abstract Exposure to Artificial Light At Night (ALAN) results in a disruption of the circadian
system, which is deleterious to health. In industrialized countries, 75% of the total workforce …
system, which is deleterious to health. In industrialized countries, 75% of the total workforce …
2016 IMS Recommendations on women's midlife health and menopause hormone therapy
RJ Baber, N Panay, A Fenton - Climacteric, 2016 - Taylor & Francis
Abstract The International Menopause Society (IMS) has produced these new 2016
recommendations on women's midlife health and menopause hormone therapy (MHT) to …
recommendations on women's midlife health and menopause hormone therapy (MHT) to …
A review of human physiological responses to light: implications for the development of integrative lighting solutions
Architectural lighting has potent biological effects but applied lighting practices that
capitalize on this potential have been limited. In this review, we endeavor to consolidate and …
capitalize on this potential have been limited. In this review, we endeavor to consolidate and …
[HTML][HTML] Interconnections between circadian clocks and metabolism
Circadian rhythms evolved through adaptation to daily light/dark changes in the
environment; they are believed to be regulated by the core circadian clock interlocking …
environment; they are believed to be regulated by the core circadian clock interlocking …
[HTML][HTML] Transkingdom control of microbiota diurnal oscillations promotes metabolic homeostasis
All domains of life feature diverse molecular clock machineries that synchronize
physiological processes to diurnal environmental fluctuations. However, no mechanisms are …
physiological processes to diurnal environmental fluctuations. However, no mechanisms are …