Crosstalk of inflammatory cytokines within the breast tumor microenvironment

O Habanjar, R Bingula, C Decombat… - International journal of …, 2023 - mdpi.com
Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Natural and synthetic carbohydrate-based vaccine adjuvants and their mechanisms of action

C Pifferi, R Fuentes, A Fernández-Tejada - Nature Reviews Chemistry, 2021 - nature.com
Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …

The hygiene hypothesis in autoimmunity: the role of pathogens and commensals

JF Bach - Nature Reviews Immunology, 2018 - nature.com
The incidence of autoimmune diseases has been steadily rising. Concomitantly, the
incidence of most infectious diseases has declined. This observation gave rise to the …

Can SARS-CoV-2 virus use multiple receptors to enter host cells?

LK Gadanec, KR McSweeney, T Qaradakhi… - International journal of …, 2021 - mdpi.com
The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

Toll-like receptors: significance, ligands, signaling pathways, and functions in mammals

MK Vidya, VG Kumar, V Sejian, M Bagath… - International reviews …, 2018 - Taylor & Francis
This review attempts to cover the implication of the toll-like receptors (TLRs) in controlling
immune functions with emphasis on their significance, function, regulation and expression …

Neuroinflammation: microglia and T cells get ready to tango

STT Schetters, D Gomez-Nicola… - Frontiers in …, 2018 - frontiersin.org
In recent years, many paradigms concerning central nervous system (CNS) immunology
have been challenged and shifted, including the discovery of CNS-draining lymphatic …

Immune defence against Candida fungal infections

MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Observation of Floquet-Bloch states on the surface of a topological insulator

YH Wang, H Steinberg, P Jarillo-Herrero, N Gedik - Science, 2013 - science.org
The unique electronic properties of the surface electrons in a topological insulator are
protected by time-reversal symmetry. Circularly polarized light naturally breaks time-reversal …

Deciphering the transcriptional network of the dendritic cell lineage

JC Miller, BD Brown, T Shay, EL Gautier, V Jojic… - Nature …, 2012 - nature.com
Although much progress has been made in the understanding of the ontogeny and function
of dendritic cells (DCs), the transcriptional regulation of the lineage commitment and …

mTOR regulates memory CD8 T-cell differentiation

K Araki, AP Turner, VO Shaffer, S Gangappa, SA Keller… - Nature, 2009 - nature.com
Memory CD8 T cells are a critical component of protective immunity, and inducing effective
memory T-cell responses is a major goal of vaccines against chronic infections and …