What we talk about when we talk about fat

ED Rosen, BM Spiegelman - Cell, 2014 - cell.com
There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Adipose tissue macrophages: going off track during obesity

L Boutens, R Stienstra - Diabetologia, 2016 - Springer
Inflammation originating from the adipose tissue is considered to be one of the main driving
forces for the development of insulin resistance and type 2 diabetes in obese individuals …

Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds

CF Guerrero-Juarez, PH Dedhia, S Jin… - Nature …, 2019 - nature.com
During wound healing in adult mouse skin, hair follicles and then adipocytes regenerate.
Adipocytes regenerate from myofibroblasts, a specialized contractile wound fibroblast. Here …

Adipocyte and adipogenesis

AT Ali, WE Hochfeld, R Myburgh, MS Pepper - European journal of cell …, 2013 - Elsevier
Adipocytes are the main constituent of adipose tissue and are considered to be a corner
stone in the homeostatic control of whole body metabolism. Their primary function is to …

Heterogeneity of adipose tissue in development and metabolic function

T Schoettl, IP Fischer, S Ussar - Journal of Experimental …, 2018 - journals.biologists.com
Adipose tissue is a central metabolic organ. Unlike other organs, adipose tissue is
compartmentalized into individual depots and distributed throughout the body. These …

Adipose tissue stem cells meet preadipocyte commitment: going back to the future [S]

WP Cawthorn, EL Scheller, OA MacDougald - Journal of lipid research, 2012 - ASBMB
White adipose tissue (WAT) is perhaps the most plastic organ in the body, capable of
regeneration following surgical removal and massive expansion or contraction in response …

Marrow fat and bone—new perspectives

PK Fazeli, MC Horowitz, OA MacDougald… - The Journal of …, 2013 - academic.oup.com
Context: There is growing interest in the relationship between bone mineral density, bone
strength, and fat depots. Marrow adipose tissue, a well-established component of the …

[HTML][HTML] The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells

KV Tran, O Gealekman, A Frontini, MC Zingaretti… - Cell metabolism, 2012 - cell.com
Adipose tissue expansion involves the enlargement of existing adipocytes, the formation of
new cells from committed preadipocytes, and the coordinated development of the tissue …

Regional differences in cellular mechanisms of adipose tissue gain with overfeeding

YD Tchoukalova, SB Votruba… - Proceedings of the …, 2010 - National Acad Sciences
Body fat distribution is an important predictor of the metabolic consequences of obesity, but
the cellular mechanisms regulating regional fat accumulation are unknown. We assessed …

Ontogeny and polarization of macrophages in inflammation: blood monocytes versus tissue macrophages

A Dey, J Allen, PA Hankey-Giblin - Frontiers in immunology, 2015 - frontiersin.org
The explosion of new information in recent years on the origin of macrophages in the steady-
state and in the context of inflammation has opened up numerous new avenues of …