Antioxidative and anti-inflammatory properties of cannabidiol

S Atalay, I Jarocka-Karpowicz, E Skrzydlewska - Antioxidants, 2019 - mdpi.com
Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of
Cannabis sativa L. CBD is non-psychoactive but exerts a number of beneficial …

Cannabidiol for pain treatment: focus on pharmacology and mechanism of action

J Mlost, M Bryk, K Starowicz - International journal of molecular sciences, 2020 - mdpi.com
Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …

[HTML][HTML] Molecular targets of cannabidiol in neurological disorders

CI Bih, T Chen, AVW Nunn, M Bazelot, M Dallas… - …, 2015 - Elsevier
Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …

Alternatively activated microglia and macrophages in the central nervous system

R Franco, D Fernández-Suárez - Progress in neurobiology, 2015 - Elsevier
Macrophages are important players in the fight against viral, bacterial, fungal and parasitic
infections. From a resting state they may undertake two activation pathways, the classical …

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

A Oláh, BI Tóth, I Borbíró, K Sugawara… - The Journal of …, 2014 - Am Soc Clin Investig
The endocannabinoid system (ECS) regulates multiple physiological processes, including
cutaneous cell growth and differentiation. Here, we explored the effects of the major …

Therapeutic potential of cannabidiol (CBD) for skin health and disorders

SM Baswan, AE Klosner, K Glynn… - Clinical, cosmetic and …, 2020 - Taylor & Francis
Though there is limited research confirming the purported topical benefits of cannabinoids, it
is certain that cutaneous biology is modulated by the human endocannabinoid system …

[HTML][HTML] Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

L Casares, V García, M Garrido-Rodríguez, E Millán… - Redox biology, 2020 - Elsevier
Cannabidiol (CBD) is a major non-psychotropic phytocannabinoid that attracted a great
attention for its therapeutic potential against different pathologies including skin diseases …

Molecular and cellular mechanisms of action of cannabidiol

N Martinez Naya, J Kelly, G Corna, M Golino, A Abbate… - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant
used for centuries for both recreational and medicinal purposes. CBD lacks the psychotropic …

[HTML][HTML] Cannabinoids as therapeutic agents in cancer: current status and future implications

B Chakravarti, J Ravi, RK Ganju - Oncotarget, 2014 - ncbi.nlm.nih.gov
The pharmacological importance of cannabinoids has been in study for several years.
Cannabinoids comprise of (a) the active compounds of the Cannabis sativa plant,(b) …

Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder

J Wei, TY Lambert, A Valada, N Patel, K Walker… - Nature …, 2023 - nature.com
Dynamic interactions of neurons and glia in the ventral midbrain mediate reward and
addiction behavior. We studied gene expression in 212,713 ventral midbrain single nuclei …