Predicting antigen presentation—what could we learn from a million peptides?
D Gfeller, M Bassani-Sternberg - Frontiers in immunology, 2018 - frontiersin.org
Antigen presentation lies at the heart of immune recognition of infected or malignant cells.
For this reason, important efforts have been made to predict which peptides are more likely …
For this reason, important efforts have been made to predict which peptides are more likely …
The other function: class II-restricted antigen presentation by B cells
LN Adler, W Jiang, K Bhamidipati, M Millican… - Frontiers in …, 2017 - frontiersin.org
Mature B lymphocytes (B cells) recognize antigens using their B cell receptor (BCR) and are
activated to become antibody-producing cells. In addition, and integral to the development of …
activated to become antibody-producing cells. In addition, and integral to the development of …
[HTML][HTML] Defining HLA-II ligand processing and binding rules with mass spectrometry enhances cancer epitope prediction
Increasing evidence indicates CD4+ T cells can recognize cancer-specific antigens and
control tumor growth. However, it remains difficult to predict the antigens that will be …
control tumor growth. However, it remains difficult to predict the antigens that will be …
HLA class II sequence variants influence tuberculosis risk in populations of European ancestry
G Sveinbjornsson, DF Gudbjartsson, BV Halldorsson… - Nature …, 2016 - nature.com
Mycobacterium tuberculosis infections cause 9 million new tuberculosis cases and 1.5
million deaths annually. To identify variants conferring risk of tuberculosis, we tested 28.3 …
million deaths annually. To identify variants conferring risk of tuberculosis, we tested 28.3 …
Differential scanning fluorimetry based assessments of the thermal and kinetic stability of peptide–MHC complexes
Measurements of thermal stability by circular dichroism (CD) spectroscopy have been widely
used to assess the binding of peptides to MHC proteins, particularly within the structural …
used to assess the binding of peptides to MHC proteins, particularly within the structural …
Antigen presentation and autophagy in teleost adaptive immunity
C Johnstone, E Chaves-Pozo - International Journal of Molecular …, 2022 - mdpi.com
Infectious diseases are a burden for aquaculture. Antigen processing and presentation
(APP) to the immune effector cells that fight pathogens is key in the adaptive immune …
(APP) to the immune effector cells that fight pathogens is key in the adaptive immune …
HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders
Bipolar affective disorder (BD) is a severe psychiatric illness, for which lithium (Li) is the gold
standard for acute and maintenance therapies. The therapeutic response to Li in BD is …
standard for acute and maintenance therapies. The therapeutic response to Li in BD is …
[HTML][HTML] Neutrophils-typical atypical antigen presenting cells?
D Polak, B Bohle - Immunology Letters, 2022 - Elsevier
Neutrophils are the most abundant cells of the immune system and key in combating
infections through phagocytosis, reactive oxygen species, neutrophil extracellular traps, and …
infections through phagocytosis, reactive oxygen species, neutrophil extracellular traps, and …
Absence of anti-hypocretin receptor 2 autoantibodies in post pandemrix narcolepsy cases
Background A recent publication suggested molecular mimicry of a nucleoprotein (NP)
sequence from A/Puerto Rico/8/1934 (PR8) strain, the backbone used in the construction of …
sequence from A/Puerto Rico/8/1934 (PR8) strain, the backbone used in the construction of …
The oral antigen-adjuvant fusion vaccine P-MCP-FlaC provides effective protective effect against largemouth bass ranavirus infection
Q Liu, X Huo, Q Tian, P Wang, F Zhao, C Yang… - Fish & Shellfish …, 2023 - Elsevier
Largemouth bass ranavirus (LMBV) is highly contagious and lethal to largemouth bass,
causing significant economic losses to the aquaculture industry. Oral vaccination is …
causing significant economic losses to the aquaculture industry. Oral vaccination is …