[HTML][HTML] NAFLD and chronic kidney disease

M Marcuccilli, M Chonchol - International journal of molecular sciences, 2016 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in developed countries and it is now considered a risk factor for cardiovascular disease …

Nonalcoholic fatty liver disease and type 2 diabetes: common pathophysiologic mechanisms

C Saponaro, M Gaggini, A Gastaldelli - Current diabetes reports, 2015 - Springer
Nonalcoholic fatty liver disease (NAFLD) is an independent risk factor for advanced liver
disease, type 2 diabetes (T2DM), and cardiovascular diseases. The prevalence of NAFLD in …

[HTML][HTML] Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease

A Mardinoglu, R Agren, C Kampf, A Asplund… - Nature …, 2014 - nature.com
Several liver disorders result from perturbations in the metabolism of hepatocytes, and their
underlying mechanisms can be outlined through the use of genome-scale metabolic models …

Performance of plasma biomarkers and diagnostic panels for nonalcoholic steatohepatitis and advanced fibrosis in patients with type 2 diabetes

F Bril, MJ McPhaul, MP Caulfield, VC Clark… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE The 2019 Standards of Medical Care in Diabetes suggested that patients with
nonalcoholic fatty liver disease (NAFLD) should be evaluated for liver fibrosis. However, the …

Ectopic fat, insulin resistance, and nonalcoholic fatty liver disease: implications for cardiovascular disease

CD Byrne, G Targher - Arteriosclerosis, thrombosis, and vascular …, 2014 - Am Heart Assoc
Ectopic fat accumulation in the liver causes nonalcoholic fatty liver disease (NAFLD), which
is the most common cause of chronic liver disease in Western countries. Ectopic liver lipid …

[HTML][HTML] Role of adipokines and peroxisome proliferator-activated receptors in nonalcoholic fatty liver disease

VG Giby, TA Ajith - World journal of hepatology, 2014 - ncbi.nlm.nih.gov
Intrahepatic fat deposition has been demonstrated in patients with nonalcoholic fatty liver
disease (NAFLD). Genetic and environmental factors are important for the development of …

Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) for the management of nonalcoholic fatty liver disease (NAFLD): a systematic review

X Lv, Y Dong, L Hu, F Lu, C Zhou… - … , diabetes & metabolism, 2020 - Wiley Online Library
There are no licensed drugs for nonalcoholic fatty liver disease (NAFLD), and there is a lack
of consensus on the best outcome measures for controlled trials. This systematic review …

The occurrence of hepatocellular carcinoma in different risk stratifications of clinically noncirrhotic nonalcoholic fatty liver disease

TY Lee, JC Wu, SH Yu, JT Lin, MS Wu… - International journal of …, 2017 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) may be a cause of hepatocellular carcinoma
(HCC), but its high prevalence challenges current surveillance strategies. We aimed to …

[HTML][HTML] Liver fibrosis markers of nonalcoholic steatohepatitis

H Enomoto, Y Bando, H Nakamura… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is one of the major causes of chronic liver injury.
NAFLD includes a wide range of clinical conditions from simple steatosis to nonalcoholic …

[HTML][HTML] Antibody-directed glucocorticoid targeting to CD163 in M2-type macrophages attenuates fructose-induced liver inflammatory changes

P Svendsen, JH Graversen, A Etzerodt, H Hager… - … Therapy Methods & …, 2017 - cell.com
Increased consumption of high-caloric carbohydrates contributes substantially to endemic
non-alcoholic fatty liver disease in humans, covering a histological spectrum from fatty liver …