The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …

The biological effects of cannabinoids, the major constituents of the ancient medicinal plant
Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled …

Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Covering up to January 2016 Cannabis sativa L. is a prolific, but not exclusive, producer of a
diverse group of isoprenylated resorcinyl polyketides collectively known as …

Medicinal Cannabis: History, Pharmacology, And Implications for the Acute Care Setting - PMC
Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Cannabis has been used for medicinal purposes for thousands of years. The prohibition of
cannabis in the middle of the 20th century has arrested cannabis research. In recent years …

Abstract Cannabinoid CB2 receptor (CB2R) agonists are investigated as therapeutic agents
in the clinic. However, their molecular mode-of-action is not fully understood. Here, we report …

Epidemiological studies reveal that marijuana increases the risk of cardiovascular disease
(CVD); however, little is known about the mechanism. Δ 9-tetrahydrocannabinol (Δ 9-THC) …

For centuries, hashish and marihuana, both derived from the Indian hemp Cannabis sativa
L., have been used for their medicinal, as well as, their psychotropic effects. These effects …