The teeth are vertebrate-specific, highly specialized organs performing fundamental
functions of mastication and speech, the maintenance of which is crucial for orofacial …

Oral and craniofacial tissues are uniquely adapted for continuous and intricate functioning,
including breathing, feeding, and communication. To achieve these vital processes, this …

Periodontium supports teeth in a mechanically stimulated tissue environment, where
heterogenous stem/progenitor populations contribute to periodontal homeostasis. In this …

Periodontal tissue stem cells, which play a crucial role in maintaining the homeostasis of
periodontal tissues, are found in the periodontal ligament (PDL). These cells have long been …

Periodontitis affects billions of people worldwide. To address relationships of periodontal
niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA …

Periodontal tissue supports teeth in the alveolar bone socket via fibrous attachment of the
periodontal ligament (PDL). The PDL contains periodontal fibroblasts and stem/progenitor …

Single-cell (sc) omics has become a powerful tool to unravel a tissue's cell landscape across
health and disease. In recent years, sc transcriptomic interrogation has been applied to a …

The periodontium is comprised of multiple units of mineralized and nonmineralized tissues
including the cementum on the root surface, the alveolar bone, periodontal ligament (PDL) …

Tooth eruption is a pivotal milestone for children's growth and development. This process
involves with the formation of the tooth root, the periodontal ligament (PDL) and the alveolar …

Introduction Periodontal ligament is the soft connective tissue joining the roots of teeth with
alveolar bone. The periodontal ligament presents significant cellular heterogeneity …