Novel gold and silver carbene complexes exert antitumor effects triggering the reactive oxygen species dependent intrinsic apoptotic pathway

D Iacopetta, A Mariconda, C Saturnino… - …, 2017 - Wiley Online Library
Cisplatin and other platinum‐based drugs are well‐known valid anticancer drugs. However,
during chemotherapy, the presence of numerous side effects and the onset of frequent …

Anticancer, antimicrobial and antiparasitical activities of copper(I) complexes based on N-heterocyclic carbene (NHC) ligands bearing aryl substituents

N Touj, ISA Nasr, WS Koko, TA Khan… - Journal of …, 2020 - Taylor & Francis
New benzimidazolium salts were synthesized as N-heterocyclic carbene precursors. These
NHC precursors were metallated with Cu2O and CuI in acetone and water under reflux to …

A Combined Spectroscopic and Protein Crystallography Study Reveals Protein Interactions of RhI(NHC) Complexes at the Molecular Level

IM Daubit, MP Sullivan, M John, DC Goldstone… - Inorganic …, 2020 - ACS Publications
While most Rh–N-heterocyclic carbene (NHC) complexes currently investigated in
anticancer research contain a Rh (III) metal center, an increasing amount of research is …

Sterically Demanding AgI and CuI N‐Heterocyclic Carbene Complexes: Synthesis, Structures, Steric Parameters, and Catalytic Activity

A Cervantes‐Reyes, F Rominger… - … –A European Journal, 2020 - Wiley Online Library
The synthesis and full characterization of new air‐stable AgI and CuI complexes bearing
structurally bulky expanded‐ring N‐heterocyclic carbene (erNHC) ligands is presented. The …

Unveiling Luminescent IrI and RhI N‐Heterocyclic Carbene Complexes: Structure, Photophysical Specifics, and Cellular Localization in the Endoplasmic Reticulum

IM Daubit, S Wortmann, D Siegmund… - … A European Journal, 2021 - Wiley Online Library
Abstract Complexes of RhI and IrI of the [M (COD)(NHC) X] type (where M= Rh or Ir, COD= 1,
5‐cyclooctadiene, NHC= N‐heterocyclic carbene, and X= halide) have recently shown …

Synthesis and Characterization of [(NHC)Ni(styrene)2] Complexes: Isolation of Monocarbene Nickel Complexes and Benchmarking of %VBur in (NHC)Ni-π …

S Felten, SF Marshall, AJ Groom… - …, 2018 - ACS Publications
The investigation of the stereoelectronic influence of N-aryl substituted NHC ligands on Ni
(0) is reported. The structural analysis of a family of [(NHC) Ni (styrene) 2] complexes are …

Synthesis and structures of amido-functionalized N-heterocyclic nickel (II) carbene complexes

SJ Lu, HH Yang, WJ Chang, HH Hsueh, YC Lin… - Journal of …, 2020 - Elsevier
A series of bis-bidentate nickel (II) complexes [Ni (R-bimy-CH 2 CONH) 2](bimyH=
benzimidazole; R= Me (3), Et (4), Ph (5)) bearing amido-functionalized N-heterocyclic …

Novel Carbazole‐Based N‐Heterocyclic Carbene Ligands to Access Synthetically Relevant Stilbenes in Pd‐Catalyzed Coupling Processes

TR Girase, AR Kapdi - Chemistry–An Asian Journal, 2019 - Wiley Online Library
A series of new carbazole‐based N‐heterocyclic carbene (NHC) ligands have been
synthesized in a simple and facile synthetic route and subsequently used in a Pd/carbazole …

N-Heterocyclic Carbene Adducts of Alkynyl Functionalized 1,3,2-Dithioborolanes

R Böser, L Denker, R Frank - Molecules, 2019 - mdpi.com
Alkynyl functionalized boron compounds are versatile intermediates in the areas of
medicinal chemistry, materials science, and optical materials. In particular, alkynyl boronate …

NHC‐Stabilized Inverse Crown Ethers Featuring the μ4‐Oxo [Mg4O] Core

Y Zhuang, Y Qian, D Tu, Y Li, J Liu… - European Journal of …, 2021 - Wiley Online Library
Compared to crown ethers with functions to capture metal cation, inverse crown ethers
(ICEs) with a similar cavity architecture have the alternating polarity of cationic metal ring …