Recent advances in droplet microfluidics
Y Ding, PD Howes, AJ deMello - Analytical chemistry, 2019 - ACS Publications
Prominent within this technology set are droplet-based microfluidic systems, 3 in which
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …
Droplet-based digital PCR (ddPCR) and its applications
Y Hou, S Chen, Y Zheng, X Zheng, JM Lin - TrAC Trends in Analytical …, 2023 - Elsevier
As a new generation absolute quantitive PCR technique, droplet-based digital PCR
(ddPCR) provides the benefits of high sensitivity, precision, and reproducibility. A low-cost …
(ddPCR) provides the benefits of high sensitivity, precision, and reproducibility. A low-cost …
Pushbutton-activated microfluidic dropenser for droplet digital PCR
Here, we report a portable microfluidic device to generate and dispense droplets simply
operated by pushbutton for droplet digital polymerase chain reaction (ddPCR), which is …
operated by pushbutton for droplet digital polymerase chain reaction (ddPCR), which is …
A portable and cost-effective microfluidic system for massively parallel single-cell transcriptome profiling
Single-cell technologies are becoming increasingly widespread and have been
revolutionizing our understanding of cell identity, state, diversity and function. However …
revolutionizing our understanding of cell identity, state, diversity and function. However …
A portable droplet generation system for ultra-wide dynamic range digital PCR based on a vibrating sharp-tip capillary
Monodisperse droplet has been widely used as a versatile tool in different disciplines
including biosensing. Existing methods still struggle to balance the droplet generation …
including biosensing. Existing methods still struggle to balance the droplet generation …
“SMART” digital nucleic acid amplification technologies for lung cancer monitoring from early to advanced stages
Recently, liquid biopsy based on detection of circulating nucleic acid (NA) biomarkers from
body fluids has emerged as a promising strategy for lung cancer monitoring. Considering …
body fluids has emerged as a promising strategy for lung cancer monitoring. Considering …
Microfluidic actuated and controlled systems and application for lab-on-chip in Space Life Science
Y Zhao, X Lv, X Li, N Rcheulishvili, Y Chen… - Space: Science & …, 2023 - spj.science.org
The use of space environment to carry out life science research is of great significance.
However, there are limitations in complex manipulation, research models based on …
However, there are limitations in complex manipulation, research models based on …
Negative pressure provides simple and stable droplet generation in a flow-focusing microfluidic device
NA Filatov, AA Evstrapov, AS Bukatin - Micromachines, 2021 - mdpi.com
Droplet microfluidics is an extremely useful and powerful tool for industrial, environmental,
and biotechnological applications, due to advantages such as the small volume of reagents …
and biotechnological applications, due to advantages such as the small volume of reagents …
Picoliter Droplet Generation and Dense Bead-in-Droplet Encapsulation via Microfluidic Devices Fabricated via 3D Printed Molds
Picoliter-scale droplets have many applications in chemistry and biology, such as
biomolecule synthesis, drug discovery, nucleic acid quantification, and single cell analysis …
biomolecule synthesis, drug discovery, nucleic acid quantification, and single cell analysis …
Droplet microfluidics enables tracing of target cells at the single-cell transcriptome resolution
Y Liu, S Wang, M Lyu, R Xie, W Guo, Y He, X Shi… - Bioengineering, 2022 - mdpi.com
The rapid promotion of single-cell omics in various fields has begun to help solve many
problems encountered in research, including precision medicine, prenatal diagnosis, and …
problems encountered in research, including precision medicine, prenatal diagnosis, and …