This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

The endocannabinoid system (eCB) is implicated in the mediation of both reward and
reinforcement. This is evidenced by the ability of exogenous cannabinoid drugs to produce …

Withdrawal from opiates, such as heroin or oral narcotics, is characterized by a host of
aversive physical and emotional symptoms. High rates of relapse and limited treatment …

Background The “classic” endocannabinoid (eCB) system includes the cannabinoid
receptors CB1 and CB2, the eCB ligands anandamide (AEA) and 2-arachidonoylglycerol (2 …

The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …

Addiction research has historically neglected research on women, and most studies have
been conducted on men only, with the concluding results generalized to the female …

Cannabis sativa is the most widely used illicit drug in the world. Its main psychoactive
component is delta‐9‐tetrahydrocannabinol (THC), one of over 100 phytocannabinoid …

Sex-dependent differences are frequently observed in the biological and behavioural effects
of substances of abuse, including cannabis. We recently demonstrated a modulating effect …

Long processing cycle makes vacuum assisted resin infusion molding (VARIM) only suitable
for low and medium volumes of production, and shortening of curing time is critical to …

Cannabis derivatives have become the most widely used illicit substances in developed
countries, and constitute a major health concern. The psychoactive compounds contained in …