Ochratoxin A: molecular interactions, mechanisms of toxicity and prevention at the molecular level

T Kőszegi, M Poór - Toxins, 2016 - mdpi.com
Ochratoxin A (OTA) is a widely-spread mycotoxin all over the world causing major health
risks. The focus of the present review is on the molecular and cellular interactions of OTA. In …

Toxicokinetics and toxicodynamics of ochratoxin A, an update

D Ringot, A Chango, YJ Schneider… - Chemico-biological …, 2006 - Elsevier
Ochratoxin A (OTA) is a mycotoxin produced by fungi of two genera: Penicillium and
Aspergillus. OTA has been shown to be nephrotoxic, hepatotoxic, teratogenic and …

Ochratoxin A: the continuing enigma

E O'Brien, DR Dietrich - Critical reviews in toxicology, 2005 - Taylor & Francis
The mycotoxin ochratoxin A (OTA) has been linked to the genesis of several disease states
in both animals and humans. It has been described as nephrotoxic, carcinogenic …

[HTML][HTML] The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells

GJ Schaaf, SM Nijmeijer, RFM Maas… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Balkan endemic nephropathy (BEN), a disease characterized by progressive renal fibrosis
in human patients, has been associated with exposure to ochratoxin A (OTA). This …

Ochratoxin A and zearalenone: a comparative study on genotoxic effects and cell death induced in bovine lymphocytes

MB Lioi, A Santoro, R Barbieri, S Salzano… - … /Genetic Toxicology and …, 2004 - Elsevier
Ochratoxin A (OTA) and zearalenone (ZEA), two naturally occurring contaminants of animal
feed, have been implicated in several mycotoxicoses in farm livestock but there is little …

Neurotoxicity mechanism of Ochratoxin A

F Nourbakhsh, E Tajbakhsh - Quality Assurance and Safety of Crops & …, 2021 - qascf.com
Mycotoxins, such as Ochratoxins, are widely distributed in nature and are common
contaminants of human foodstuffs. Ochratoxins are a group of mycotoxins produced by a …

Apoptosis and oxidative stress induced by ochratoxin A in rat kidney

J Petrik, T Žanić-Grubišić, K Barišić, S Pepeljnjak… - Archives of …, 2003 - Springer
Ochratoxin A (OTA) is a widespread mycotoxin produced by several species of fungi. OTA
induces a tubular-interstitial nephropathy in humans and in animals. It has been implicated …

Ochratoxin A and mitotic disruption: mode of action analysis of renal tumor formation by ochratoxin A

A Mally - Toxicological Sciences, 2012 - academic.oup.com
The mycotoxin and food contaminant ochratoxin A (OTA) is a potent renal carcinogen in
rodents, but its mode of action (MoA) is still poorly defined. In 2006, the European Food …

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression

R Nahta, F Al-Mulla, R Al-Temaimi, A Amedei… - …, 2015 - academic.oup.com
As part of the Halifax Project, this review brings attention to the potential effects of
environmental chemicals on important molecular and cellular regulators of the cancer …

Ochratoxin A-induced mutagenesis in mammalian cells is consistent with the production of oxidative stress

N Palma, S Cinelli, O Sapora, SH Wilson… - Chemical research in …, 2007 - ACS Publications
Ochratoxin A (OTA) is a widespread mycotoxin in food and a powerful nephrocarcinogen in
rats. The mutagenicity of OTA has been extensively investigated but with conflicting results …