Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD)
is a life-threatening aortic pathology associated with high morbidity and mortality. Initiators of …

Genetic predisposition and risk factors such as hypertension and smoking can instigate the
development of thoracic aortic aneurysm (TAA), which can lead to highly lethal aortic wall …

Aims Whether changes in endothelial tight junctions (TJs) lead to the formation of thoracic
aortic aneurysm and dissection (TAAD) and serve as an early indicator and therapeutic …

Aortic dissection (AD) is a fatal disease that accounts for a large proportion of aortic-related
deaths and has an incidence of about 3–4 per 100,000 individuals every year. Recent …

Granulocyte-macrophage colony-stimulating factor (GM-CSF) and inteleukin-3 (IL-3) have
long been known as mediators of emergency myelopoiesis, but recent evidence has …

Genetically triggered thoracic aortic aneurysms (TAAs) are usually considered to exhibit
minimal levels of inflammation. However, emerging data demonstrate that specific features …

Rationale: Thoracic aortic aneurysm (TAA) leads to substantial mortality worldwide. Familial
and syndromic TAAs are highly correlated with genetics. However, the incidence of sporadic …

Melatonin functions as an endogenous protective molecule in multiple vascular diseases,
whereas its effects on thoracic aortic aneurysm and dissection (TAAD) and underlying …

Aortic dissection (AD) is one of the most dangerous forms of vascular disease, characterized
by endometrial rupture and intramural hematoma formation. Generally, the pathological …

The mechanistic basis for the formation of aortic aneurysms and dissection needs to be
elucidated to facilitate the development of effective medications. β-Aminopropionitrile …