Proteomics Impact on Cell Biology to Resolve Cell Structure and Function
JJM Bergeron - Molecular & Cellular Proteomics, 2024 - ASBMB
The acceleration of advances in proteomics has enabled integration with imaging at the EM
and light microscopy levels, cryo-EM of protein structures, and artificial intelligence with …
and light microscopy levels, cryo-EM of protein structures, and artificial intelligence with …
Effect of α-tubulin acetylation on the doublet microtubule structure
Acetylation of α-tubulin at the lysine 40 residue (αK40) by αTAT1/MEC-17 acetyltransferase
modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures …
modulates microtubule properties and occurs in most eukaryotic cells. Previous literatures …
DomainFit: Identification of protein domains in cryo-EM maps at intermediate resolution using AlphaFold2-predicted models
Cryoelectron microscopy (cryo-EM) has revolutionized the structural determination of
macromolecular complexes. With the paradigm shift to structure determination of highly …
macromolecular complexes. With the paradigm shift to structure determination of highly …
A network of interacting ciliary tip proteins with opposing activities imparts slow and processive microtubule growth
HAJ Saunders, CM van den Berg, R Hoogebeen… - bioRxiv, 2024 - biorxiv.org
Cilia are essential motile or sensory organelles found on many eukaryotic cells. Their
formation and function rely on axonemal microtubules, which exhibit very slow dynamics …
formation and function rely on axonemal microtubules, which exhibit very slow dynamics …