Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …

Frataxin, a highly conserved protein found in prokaryotes and eukaryotes, is required for
efficient regulation of cellular iron homeostasis. Humans with a frataxin deficiency have the …

The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2)
highlights the need for coordinated research to combat COVID-19. A particularly important …

A major challenge of computational protein design is the creation of novel proteins with
arbitrarily chosen three-dimensional structures. Here, we used a general computational …

To comply with the trend toward green and sustainable development of the fine chemical
industry, multitudinous promising technologies (eg, photocatalysis and electrocatalysis) are …

A class of translation inhibitors, exemplified by the natural product rocaglamide A (RocA),
isolated from Aglaia genus plants, exhibits antitumor activity by clamping eukaryotic …

We demonstrate for different protein samples that 2D 1H− 15N correlation NMR spectra can
be recorded in a few seconds of acquisition time using a new band-selective optimized flip …

The solution structure of a human immunodeficiency virus type-1 (HIV-1) Rev peptide bound
to stem-loop IIB of the Rev response element (RRE) RNA was solved by nuclear magnetic …

Ubiquitin is a versatile cellular signaling molecule that can form polymers of eight different
linkages, and individual linkage types have been associated with distinct cellular functions …

Measurement of exchange rates between water and NH protons by magnetization transfer
methods is often complicated by artifacts, such as intramolecular NOEs, and/or TOCSY …