This review describes the diffusion model for light transport in tissues and the medical
applications of diffuse light. Diffuse optics is particularly useful for measurement of tissue …

We present a review of methods for the forward and inverse problems in optical tomography.
We limit ourselves to the highly scattering case found in applications in medical imaging …

A recent development in biomedical imaging is the non-invasive mapping of molecular
events in intact tissues using fluorescence. Underpinning to this development is the …

Fluorescence sampling of cellular function is widely used in all aspects of biology, allowing
the visualization of cellular and sub-cellular biological processes with spatial resolutions in …

Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

Diffuse optical tomography (DOT) is an ongoing medical imaging modality in which tissue is
illuminated by near-infrared light from an array of sources, the multiply-scattered light which …

There is a wealth of new fluorescent reporter technologies for tagging of many cellular and
subcellular processes in vivo. This imposed contrast is now captured with an increasing …

Systematic efforts are under way to develop novel technologies that would allow molecular
sensing in intact organisms in vivo. Using near-infrared fluorescent molecular beacons and …

A tutorial introduction to diffuse light transport is presented. The basic analytic equations of
time-resolved, steady-state and modulated light transport are introduced. The perturbation …

We present a normalized Born expansion that facilitates fluorescence reconstructions in
turbid, tissuelike media. The algorithm can be particularly useful for tissue investigations of …