Obesity: pathophysiology and management

KM Gadde, CK Martin, HR Berthoud… - Journal of the American …, 2018 - jacc.org
Obesity continues to be among the top health concerns across the globe. Despite our failure
to contain the high prevalence of obesity, we now have a better understanding of its …

Obesity and cardiovascular disease

FB Ortega, CJ Lavie, SN Blair - Circulation research, 2016 - Am Heart Assoc
The prevalence of obesity has increased worldwide over the past few decades. In 2013, the
prevalence of obesity exceeded the 50% of the adult population in some countries from …

Association of cardiorespiratory fitness with long-term mortality among adults undergoing exercise treadmill testing

K Mandsager, S Harb, P Cremer, D Phelan… - JAMA network …, 2018 - jamanetwork.com
Importance Adverse cardiovascular findings associated with habitual vigorous exercise
have raised new questions regarding the benefits of exercise and fitness. Objective To …

Precision exercise medicine: understanding exercise response variability

R Ross, BH Goodpaster, LG Koch… - British journal of sports …, 2019 - bjsm.bmj.com
There is evidence from human twin and family studies as well as mouse and rat selection
experiments that there are considerable interindividual differences in the response of …

Body fat distribution and risk of cardiovascular disease: an update

JP Després - Circulation, 2012 - Am Heart Assoc
Epidemiological, clinical, and mechanistic preclinical studies conducted in the field of
cardiovascular medicine have led to remarkable progress in our understanding of …

Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for …

CE Garber, B Blissmer, MR Deschenes… - 2011 - academiccommons.columbia.edu
The purpose of this Position Stand is to provide guidance to professionals who counsel and
prescribe individualized exercise to apparently healthy adults of all ages. These …

Fitness vs. fatness on all-cause mortality: a meta-analysis

VW Barry, M Baruth, MW Beets, JL Durstine… - Progress in …, 2014 - Elsevier
The purpose of this study was to quantify the joint association of cardiorespiratory fitness
(CRF) and weight status on mortality from all causes using meta-analytical methodology …

Obesity and cardiovascular diseases: implications regarding fitness, fatness, and severity in the obesity paradox

CJ Lavie, PA McAuley, TS Church, RV Milani… - Journal of the American …, 2014 - jacc.org
Obesity has been increasing in epidemic proportions, with a disproportionately higher
increase in morbid or class III obesity, and obesity adversely affects cardiovascular (CV) …

Relation of smoking with total mortality and cardiovascular events among patients with diabetes mellitus: a meta-analysis and systematic review

A Pan, Y Wang, M Talaei, FB Hu - Circulation, 2015 - Am Heart Assoc
Background—The prevalence of smoking in diabetic patients remains high, and reliable
quantification of the excess mortality and morbidity risks associated with smoking is …

Effects of aerobic and resistance training on hemoglobin A1c levels in patients with type 2 diabetes: a randomized controlled trial

TS Church, SN Blair, S Cocreham, N Johannsen… - Jama, 2010 - jamanetwork.com
Context Exercise guidelines for individuals with diabetes include both aerobic and
resistance training although few studies have directly examined this exercise combination …