Why should we measure free 25 (OH) vitamin D?

O Tsuprykov, X Chen, CF Hocher, R Skoblo… - The Journal of steroid …, 2018 - Elsevier
Vitamin D, either in its D 2 or D 3 form, is essential for normal human development during
intrauterine life, kidney function and bone health. Vitamin D deficiency has also been linked …

[HTML][HTML] Blood biomarkers of vitamin D status

JE Zerwekh - The American journal of clinical nutrition, 2008 - Elsevier
In the past quarter century, more than 50 metabolites of vitamin D have been described. To
date, only a few of these have been quantified in blood, but this has widened our …

Vitamin D and cancer risk and mortality: state of the science, gaps, and challenges

AM Mondul, SJ Weinstein, TM Layne… - Epidemiologic …, 2017 - academic.oup.com
There has been substantial enthusiasm recently regarding the potential role of vitamin D in
the primary and secondary prevention of cancer. Laboratory studies demonstrate a range of …

Vitamin D–binding protein modifies the vitamin D–bone mineral density relationship

CE Powe, C Ricciardi, AH Berg… - Journal of Bone and …, 2011 - academic.oup.com
Studies examining the relationship between total circulating 25‐hydroxyvitamin D [25 (OH)
D] levels and bone mineral density (BMD) have yielded mixed results. Vitamin D–binding …

[HTML][HTML] The relation between acute changes in the systemic inflammatory response and plasma 25-hydroxyvitamin D concentrations after elective knee arthroplasty

D Reid, BJ Toole, S Knox, D Talwar, J Harten… - The American journal of …, 2011 - Elsevier
Background: Studies indicate that low plasma 25-hydroxyvitamin D [25 (OH) D] is associated
with a range of disease processes, many of which are inflammatory. However, other lipid …

Dietary reference values for vitamin D

EFSA Panel on Dietetic Products, Nutrition and … - EFSA …, 2016 - Wiley Online Library
Following a request from the European Commission, the EFSA Panel on Dietetic Products,
Nutrition and Allergies (NDA) derived dietary reference values (DRV s) for vitamin D. The …

Vitamin D metabolites in captivity? Should we measure free or total 25 (OH) D to assess vitamin D status?

D Bikle, R Bouillon, R Thadhani… - The Journal of steroid …, 2017 - Elsevier
There is general consensus that serum 25 (OH) D is the best biochemical marker for
nutritional vitamin D status. Whether free 25 (OH) D would be a better marker than total 25 …

[HTML][HTML] Vitamin D across the lifecycle: physiology and biomarkers

A Prentice, GR Goldberg, I Schoenmakers - The American journal of …, 2008 - Elsevier
The field of vitamin D public health research has a pressing need to define sensitive and
specific predictors of vitamin D status that can be used to determine whether an individual or …

The role of vitamin D in reducing the risk of metabolic disturbances that cause cardiovascular diseases

ZH Al-Oanzi, FO Alenazy, HH Alhassan… - Journal of …, 2023 - mdpi.com
Among the most common problems facing public health today is a lack of vitamin D, which
plays a role in the physiological processes of chronic illness conditions. Vitamin D deficiency …

Epidemiology of vitamin D in health and disease

S Wang - Nutrition research reviews, 2009 - cambridge.org
Results from ecological, case–control and cohort studies have shown that vitamin D reduces
the risk of bone fracture, falls, autoimmune diseases, type 2 diabetes, CVD and cancer …