Role of the autonomic nervous system in modulating cardiac arrhythmias

MJ Shen, DP Zipes - Circulation research, 2014 - Am Heart Assoc
The autonomic nervous system plays an important role in the modulation of cardiac
electrophysiology and arrhythmogenesis. Decades of research has contributed to a better …

Exercise is the real polypill

C Fiuza-Luces, N Garatachea, NA Berger… - Physiology, 2013 - journals.physiology.org
The concept of a “polypill” is receiving growing attention to prevent cardiovascular disease.
Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free …

Cardiac innervation and sudden cardiac death

K Fukuda, H Kanazawa, Y Aizawa, JL Ardell… - Circulation …, 2015 - Am Heart Assoc
Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …

Heart rate variability–a historical perspective

GE Billman - Frontiers in physiology, 2011 - frontiersin.org
Heart rate variability (HRV), the beat-to-beat variation in either heart rate or the duration of
the R–R interval–the heart period, has become a popular clinical and investigational tool …

Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction

MT La Rovere, JT Bigger, FI Marcus, A Mortara… - The Lancet, 1998 - thelancet.com
Background Experimental evidence suggests that autonomic markers such as heart-rate
variability and baroreflex sensitivity (BRS) may contribute to post-infarction risk stratification …

Clinical neurocardiology defining the value of neuroscience‐based cardiovascular therapeutics

K Shivkumar, OA Ajijola, I Anand… - The Journal of …, 2016 - Wiley Online Library
The autonomic nervous system regulates all aspects of normal cardiac function, and is
recognized to play a critical role in the pathophysiology of many cardiovascular diseases. As …

The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment

DL Musselman, DL Evans… - Archives of general …, 1998 - jamanetwork.com
This article reviews the burgeoning literature on the relationship of mood disorders and
heart disease. Major depression and depressive symptoms, although commonly …

Task force on sudden cardiac death of the European Society of Cardiology

SG Priori, E Aliot, C Blomstrom-Lundqvist… - European heart …, 2001 - academic.oup.com
The members of the Task Force on Sudden Death dedicate this paper to the memory of our
former friend and colleague, Professor Ronald WF Campbell. Ronnie spent his life working …

Baroreflex sensitivity: measurement and clinical implications

MT La Rovere, GD Pinna… - Annals of noninvasive …, 2008 - Wiley Online Library
Alterations of the baroreceptor‐heart rate reflex (baroreflex sensitivity, BRS) contribute to the
reciprocal reduction of parasympathetic activity and increase of sympathetic activity that …

Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction.

E Vanoli, GM De Ferrari, M Stramba-Badiale… - Circulation …, 1991 - Am Heart Assoc
The interest for the antifibrillatory effect of vagal stimulation has been largely limited by the
fact that this concept seemed restricted to acute experiments in anesthetized animals. To …