The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The pathobiology of human fungal infections

GD Brown, ER Ballou, S Bates, EM Bignell… - Nature Reviews …, 2024 - nature.com
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Understanding how microorganisms respond to acid pH is central to their control and successful exploitation

PA Lund, D De Biase, O Liran, O Scheler… - Frontiers in …, 2020 - frontiersin.org
Microbes from the three domains of life, Bacteria, Archaea, and Eukarya, share the need to
sense and respond to changes in the external and internal concentrations of protons. When …

[HTML][HTML] Cell biology of Candida albicans–host interactions

A da Silva Dantas, KK Lee, I Raziunaite… - Current opinion in …, 2016 - Elsevier
Highlights•The cell biology of Candida albicans is adapted both for life as a commensal and
as a pathogen.•C. albicans can either downregulate or upregulate virulence properties in …

Bacterial-fungal metabolic interactions within the microbiota and their potential relevance in human health and disease: a short review

A Lapiere, ML Richard - Gut Microbes, 2022 - Taylor & Francis
The composition of the microbiota is the focus of many recent publications describing the
effects of the microbiota on host health. In recent years, research has progressed further …

Candida albicans can foster gut dysbiosis and systemic inflammation during HIV infection

SD Zaongo, J Ouyang, S Isnard, X Zhou… - Gut …, 2023 - Taylor & Francis
Candida albicans (C. albicans) is a ubiquitous fungal commensal component of the human
microbiota, and under certain circumstances, such as during an immunocompromised state …

Sugar Sensing and Signaling in Candida albicans and Candida glabrata

M Van Ende, S Wijnants, P Van Dijck - Frontiers in microbiology, 2019 - frontiersin.org
Candida species, such as Candida albicans and Candida glabrata, cause infections at
different host sites because they adapt their metabolism depending on the available …

Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …

Effect of Acetic Acid and Lactic Acid at Low pH in Growth and Azole Resistance of Candida albicans and Candida glabrata

A Lourenço, NA Pedro, SB Salazar… - Frontiers in microbiology, 2019 - frontiersin.org
Successful colonization of the acidic vaginal niche by C. glabrata and C. albicans depends
on their ability to cope with the presence of lactic and acetic acids produced by commensal …

[HTML][HTML] Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation

MD Lenardon, P Sood, HC Dorfmueller, AJP Brown… - The Cell Surface, 2020 - Elsevier
Despite the importance of fungal cell walls as the principle determinant of fungal
morphology and the defining element determining fungal interactions with other cells, few …