Adipocyte-derived small extracellular vesicles from patients with Alzheimer disease carry miRNAs predicted to target the CREB signaling pathway in neurons
Alzheimer disease (AD) is characterized by amyloid-β (Aβ) plaques, neurofibrillary tangles,
synaptic dysfunction, and progressive dementia. Midlife obesity increases the risk of …
synaptic dysfunction, and progressive dementia. Midlife obesity increases the risk of …
Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions
G Ribaudo, A Gianoncelli - Mini Reviews in Medicinal …, 2024 - ingentaconnect.com
This Perspective provides an updated overview on the involvement of phosphodiesterase
(PDE) isoforms and of the corresponding inhibitors in neurological disorders, including …
(PDE) isoforms and of the corresponding inhibitors in neurological disorders, including …
PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF ALZHEIMER'S DISEASE.
P Chandra, H Sharma - Indian Drugs, 2024 - search.ebscohost.com
Cognitive decline with aging is a concern, particularly in neurodegenerative and mental
diseases. Cognitive enhancers focus on cholinergic and monoaminergic systems, but …
diseases. Cognitive enhancers focus on cholinergic and monoaminergic systems, but …
Cardioprotective Effects of Phlorizin on Hyperlipidemia-induced Myocardial Injury: Involvement of Suppression in Pyroptosis via Regulating HK1/NLRP3/Caspase-1 …
Y Zhang, Y Wang, X Cheng, H Guo, D Ma… - Applied Biochemistry …, 2024 - Springer
Hyperlipidemia (HLP) is a prevalent and intricate condition that plays a pivotal role in
impairing heart function. The primary objective of this study was to assess the lipid-lowering …
impairing heart function. The primary objective of this study was to assess the lipid-lowering …
Identification of vilazodone as a novel plasminogen activator inhibitor to overcome Alzheimer's disease through virtual screening, molecular dynamics simulation, and …
W Sun, X Sheng, P Li, R Li, Z Guo, H Lin… - Archiv der …, 2024 - Wiley Online Library
Urokinase‐type plasminogen activator (PLAU), a member of the S1 serine peptidase family
in Clan PA, plays a crucial role in the conversion of plasminogen into active plasmin …
in Clan PA, plays a crucial role in the conversion of plasminogen into active plasmin …