The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …

CaMKII and CaMKIV are calcium/calmodulin-dependent kinases playing a rudimentary role
in many regulatory processes in the organism. These kinases attract increasing interest due …

Binge alcohol consumption induces discrete social and arousal disturbances in human
populations that promote increased drinking and accelerate the progression of Alcohol Use …

Alcohol consumption afflicts men and women differently. However, the underlying neuronal
mechanisms that contribute to the difference are mostly unexplored. Although more men …

Withdrawal from chronic alcohol drinking can cause depression, leading to an inability to
function in daily life and an increased risk for relapse to harmful drinking. Understanding the …

Anxiety disorders often co-occur with alcohol use disorders, but the mechanisms underlying
this comorbidity remain elusive. Previously, we reported that rats withdrawn from chronic …

Hypofunction of the serotonergic (5-HT) system has close relationship with the symptoms in
major depressive disorders (MDD), however, the underlying neural circuitry mechanisms are …

Rationale Preclinical studies report attenuated ethanol-induced conditioned taste aversion
(CTA) following chronic ethanol exposure, suggesting that tolerance develops to the …

Abstract Ethnopharmacological relevance Huang-Lian-Jie-Du decoction (HLJD), a
traditional Chinese medicine prescription, has been implicated as effective in treating colitis …

Observational studies have previously reported an association between depression and
certain female reproductive disorders. However, the causal relationships between …