In recent years, there has been a great deal of attention toward the field of free radical
chemistry. Free radicals reactive oxygen species and reactive nitrogen species are …

This review article focuses on a critical survey of the main available information on the UVB
and UVA oxidative reactions to cellular DNA as the result of direct interactions of UV …

Free radical damage is an important factor in many pathological and toxicological
processes. Despite extensive research efforts in biomarkers in recent years, yielding …

8-hydroxy-2′-deoxyguanosine (8-OH-dG) was first reported in 1984 as a major form of
oxidative DNA damage product by heated sugar, Fenton-type reagents and X-irradiation in …

Chronic inflammation plays a multifaceted role in carcinogenesis. Mounting evidence from
preclinical and clinical studies suggests that persistent inflammation functions as a driving …

Recent studies have clarified that reactive oxygen species (ROS) are involved in a diversity
of biological phenomena including radiation damage, carcinogenesis, ischemia–reperfusion …

Aims/hypothesis: We examined the pancreatic islet lesions in Japanese patients with Type II
diabetes mellitus to determine if the damage was related to oxidative stress. Methods …

Olive fruit is a significant and promising source of potential bioactive compounds such as
oleuropein and hydroxytyrosol. Oleuropein is the ester of elenolic acid and 3, 4 …

The nitration of free tyrosine or protein tyrosine residues generates 3-nitrotyrosine the
detection of which has been utilised as a footprint for the in vivo formation of peroxynitrite …

The history of oxygen free radicals began approximately 2× 109 years ago, with the
appearance of the first blue-green algae, the most primitive organisms capable of …