ABSTRACT Introduction: Antiepileptic drugs (AEDs) are the cornerstone of treatment of
patients with epilepsy, and there are presently 27 licensed AEDs making AEDs among the …

Given the distinctive characteristics of both epilepsy and antiepileptic drugs (AEDs),
therapeutic drug monitoring (TDM) can make a significant contribution to the field of …

Epilepsy often develops in patients with glioma, and the two conditions share common
pathogenic mechanisms. Altered expression of glutamate transporters, including the cystine …

Background and objective Laboratories sometimes use different reference ranges for the
same antiepileptic drug (AED), particularly for new and poorly investigated drugs. This may …

Epilepsies occur across the entire age range, and their incidence peaks in the first years of
life and in the elderly. Therefore, antiepileptic drugs (AEDs) are commonly used at the …

This review focuses on the evolution of approaches to dosing of antiepileptic drugs (AEDs)
in clinical practice through history. There has been a shift in the view of treatment of …

Despite being one of the most commonly prescribed antiepileptic drugs, levetiracetam is
marketed in oral and intravenous dosage forms, which are associated to drug-drug …

Purpose: Levetiracetam (LEV) is a broad spectrum antiepileptic drug (AED) that has a more
favorable side effect profile compared to older AEDs. Therapeutic drug monitoring (TDM) of …

Abstract Therapeutic Drug Monitoring (TDM) of anti-epileptic drugs (AEDs) is not routinely
performed, although this can guide the dosage regimen to achieve greater efficacy and …

Levetiracetam (LEV) is an anti‐epileptic drug approved for use in various populations. The
pharmacokinetic (PK) behavior of LEV may be altered in the elderly and patients with renal …