EDC-2: the Endocrine Society's second scientific statement on endocrine-disrupting chemicals

AC Gore, VA Chappell, SE Fenton, JA Flaws… - Endocrine …, 2015 - academic.oup.com
Abstract The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to
the scientific community about how environmental endocrine-disrupting chemicals (EDCs) …

Bisphenol A and hormone-associated cancers: current progress and perspectives

H Gao, BJ Yang, N Li, LM Feng, XY Shi, WH Zhao… - Medicine, 2015 - journals.lww.com
Bisphenol A (BPA), a carbon-based synthetic compound, exhibits hormone-like properties
and is present ubiquitously in the environment and in human tissues due to its widespread …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

Endocrine disruptors from the environment affecting breast cancer

GM Calaf, R Ponce-Cusi, F Aguayo… - Oncology …, 2020 - spandidos-publications.com
Evaluation of carcinogenic substances from the environment is a challenge for scientists.
Recently, a novel approach based on 10 key characteristics of human carcinogens …

Bisphenol A replacement chemicals, BPF and BPS, induce protumorigenic changes in human mammary gland organoid morphology and proteome

J Winkler, P Liu, K Phong, JH Hinrichs… - Proceedings of the …, 2022 - National Acad Sciences
Environmental chemicals such as bisphenol A (BPA) are thought to contribute to
carcinogenesis through their endocrine-disrupting properties. Due to accumulating evidence …

Endocrine-disrupting chemicals (EDCs) and cancer: new perspectives on an old relationship

R Modica, E Benevento, A Colao - Journal of Endocrinological …, 2023 - Springer
Purpose Environmental endocrine-disrupting chemicals (EDCs) are a mixture of chemical
compounds capable to interfere with endocrine axis at different levels and to which …

Effects of perinatal exposure to BPA, BPF and BPAF on liver function in male mouse offspring involving in oxidative damage and metabolic disorder

Z Meng, S Tian, J Yan, M Jia, S Yan, R Li, R Zhang… - Environmental …, 2019 - Elsevier
Bisphenols (BPs) are common environmental pollutants that are ubiquitous in the natural
environment and can affect human health. In this study, we explored the effects of perinatal …

[HTML][HTML] The new biology of estrogen-induced apoptosis applied to treat and prevent breast cancer

VC Jordan - Endocrine-related cancer, 2015 - ncbi.nlm.nih.gov
The successful use of high dose synthetic estrogens to treat post-menopausal metastatic
breast cancer, is the first effective “chemical therapy” proven in clinical trial to treat any …

Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo

P Deb, A Bhan, I Hussain, KI Ansari, SA Bobzean… - Gene, 2016 - Elsevier
HOXB9 is a homeobox-containing gene that plays a key role in mammary gland
development and is associated with breast and other types of cancer. Here, we demonstrate …

[HTML][HTML] Endocrine disruption of the epigenome: a breast cancer link

KC Knower, SQ To, YK Leung, SM Ho… - Endocrine-related …, 2014 - ncbi.nlm.nih.gov
The heritable component of breast cancer accounts for only a small proportion of total
incidences. Environmental and lifestyle factors are therefore considered to among the major …