Physiological and pharmaceutical considerations for rectal drug formulations

S Hua - Frontiers in pharmacology, 2019 - frontiersin.org
Although the oral route is the most convenient route for drug administration, there are a
number of circumstances where this is not possible from either a clinical or pharmaceutical …

Recent advances in polymer-based vaginal drug delivery systems

T Osmałek, A Froelich, B Jadach, A Tatarek… - Pharmaceutics, 2021 - mdpi.com
The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

Novel drug delivery system of luliconazole-Formulation and characterisation

GR Kapileshwari, AR Barve, L Kumar, PJ Bhide… - Journal of Drug Delivery …, 2020 - Elsevier
Dermatophytes, a group of fungal species causing superficial fungal infections possess a
major health problem in a wide group of people. Various approaches have been used in …

Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis

M Carone, MR Spalinger, RA Gaultney… - Nature …, 2023 - nature.com
Ulcerative colitis is a chronic inflammatory bowel disease that strongly affects patient quality
of life. Side effects of current therapies necessitate new treatment strategies that maximise …

Evaluation of biodegradable PVA-based 3D printed carriers during dissolution

B Basa, G Jakab, N Kállai-Szabó, B Borbás, V Fülöp… - Materials, 2021 - mdpi.com
The presence of additive manufacturing, especially 3D printing, has the potential to
revolutionize pharmaceutical manufacturing owing to the distinctive capabilities of …

Eudragit RS100 based microsponges for dermal delivery of clobetasol propionate in psoriasis management

N Devi, S Kumar, M Prasad, R Rao - Journal of drug delivery science and …, 2020 - Elsevier
Clobetasol propionate (CP), a super potent dihalogenated topical corticosteroid for
psoriasis, displays common side effects like allergic contact dermatitis, steroid acne, skin …

Resolving acne with optimized adapalene microspongeal gel, in vivo and clinical evaluations

RM Yehia, MH Teaima, MH Ragaie, MM Elmazar… - Scientific Reports, 2024 - nature.com
In our pursuit of enhancing acne treatment while minimizing side effects, we developed
tailored Adapalene microsponges (MS) optimized using a Box–Behnken design 33. The …

[PDF][PDF] Screening of adapalene microsponges fabrication parameters with insight on the in vitro biological effectiveness

RM Yehia, DA Attia, MM Elmazar… - Drug Design …, 2022 - Taylor & Francis
Purpose The objective of the present study was to scrutinize the microsponges (MS) as a
carrier system using Adapalene (ADA) as a model drug. Methods Data modelling was …

Understanding the effects of associated factors in the development of microsponge-based drug delivery: a statistical quality by design (QbD) approach towards …

S Karmakar, S Poddar, J Khanam - AAPS PharmSciTech, 2022 - Springer
The investigation aims to prepare, identify, analyse, and understand the effects of different
variables and constant factors associated with developing drug-loaded microsponge …

In vitro and in vivo evaluation of oral controlled release formulation of bcs class i drug using polymer matrix system

M Arafat, M Sarfraz, MF Bostanudin, A Esmaeil… - Pharmaceuticals, 2021 - mdpi.com
Diltiazem hydrochloride is a calcium channel blocker, which belongs to the family of
benzothiazepines. It is commonly used to treat hypertension and atrial fibrillation. Even …