Bidirectional microglia–neuron communication in health and disease
Z Szepesi, O Manouchehrian, S Bachiller… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …
The biphasic function of microglia in ischemic stroke
Microglia are brain resident macrophages originated from primitive progenitor cells in the
yolk sac. Microglia can be activated within hours and recruited to the lesion site …
yolk sac. Microglia can be activated within hours and recruited to the lesion site …
Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
DP Schafer, EK Lehrman, AG Kautzman, R Koyama… - Neuron, 2012 - cell.com
Microglia are the resident CNS immune cells and active surveyors of the extracellular
environment. While past work has focused on the role of these cells during disease, recent …
environment. While past work has focused on the role of these cells during disease, recent …
Physiology of microglia
H Kettenmann, UK Hanisch, M Noda… - Physiological …, 2011 - journals.physiology.org
Microglial cells are the resident macrophages in the central nervous system. These cells of
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …
mesodermal/mesenchymal origin migrate into all regions of the central nervous system …
Priming of microglia with IFN‐γ impairs adult hippocampal neurogenesis and leads to depression‐like behaviors and cognitive defects
J Zhang, H He, Y Qiao, T Zhou, H He, S Yi, L Zhang… - Glia, 2020 - Wiley Online Library
Neuroinflammation driven by interferon‐gamma (IFN‐γ) and microglial activation has been
linked to neurological disease. However, the effects of IFN‐γ‐activated microglia on …
linked to neurological disease. However, the effects of IFN‐γ‐activated microglia on …
Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention
Traumatic brain injury (TBI) remains one of the leading causes of mortality and morbidity
worldwide, yet despite extensive efforts to develop neuroprotective therapies for this …
worldwide, yet despite extensive efforts to develop neuroprotective therapies for this …
Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation
Recent clinical studies indicate that traumatic brain injury (TBI) produces chronic and
progressive neurodegenerative changes leading to late neurologic dysfunction, but little is …
progressive neurodegenerative changes leading to late neurologic dysfunction, but little is …
[HTML][HTML] Microglial activation and chronic neurodegeneration
Microglia, the resident innate immune cells in the brain, have long been implicated in the
pathology of neurodegenerative diseases. Accumulating evidence points to activated …
pathology of neurodegenerative diseases. Accumulating evidence points to activated …
The adverse effects of air pollution on the nervous system
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
Optical coherence tomography as retinal imaging biomarker of neuroinflammation/neurodegeneration in systemic disorders in adults and children
The retina and the optic nerve are considered extensions of the central nervous system
(CNS) and thus can serve as the window for evaluation of CNS disorders. Spectral domain …
(CNS) and thus can serve as the window for evaluation of CNS disorders. Spectral domain …