Proteins at interfaces play important roles in cell biology, immunology, bioengineering, and
biomimetic material design. Many biological processes are based on interfacial protein …

Peptides and peptide-conjugates, comprising natural and synthetic building blocks, are an
increasingly popular class of biomaterials. Self-assembled nanostructures based on …

The amyloid aggregation of α-synuclein (α S), related to Parkinson's disease, can be
catalyzed by lipid membranes. Despite the importance of lipid surfaces, the 3D-structure and …

The use of methods at molecular scale for the discovery of new potential active ligands, as
well as previously unknown binding sites for target proteins, is now an established reality …

Injection of nanoparticles (NP) into the bloodstream leads to the formation of a so-called
“nano–bio” interface where dynamic interactions between nanoparticle surfaces and blood …

Peptide self-assembly is the process by which peptide molecules aggregate into low
dimensional (1D, 2D) or 3D ordered materials with potential applications ranging from drug …

The aggregation of peptides into amyloid fibrils has been linked to ageing-related diseases,
such as Alzheimer's and type 2 diabetes. Interfaces, particularly those with large …

Peptides have become excellent platforms for the design of peptide–nanoparticle hybrid
superstructures, owing to their self-assembly and binding/recognition capabilities. Morover …

Nanoparticles (NPs) exposed to a biological milieu will strongly interact with proteins,
forming “coronas” on the surfaces of the NPs. The protein coronas (PCs) affect the properties …

The aberrant aggregation of amyloid-β (Aβ) peptides in the brain has been recognized as
the major hallmark of Alzheimer's disease (AD). Thus, the inhibition and dissociation of Aβ …