Macrophage phagocytosis after spinal cord injury: when friends become foes
After spinal cord injury, macrophages can exert either beneficial or detrimental effects
depending on their phenotype. Aside from their critical role in inflammatory responses …
depending on their phenotype. Aside from their critical role in inflammatory responses …
Macrophagic and microglial complexity after neuronal injury
F Mesquida-Veny, JA Del Río, A Hervera - Progress in neurobiology, 2021 - Elsevier
Central nervous system (CNS) injuries do not heal properly in contrast to normal tissue
repair, in which functional recovery typically occurs. The reason for this dichotomy in wound …
repair, in which functional recovery typically occurs. The reason for this dichotomy in wound …
Berberine-loaded MSC-derived sEVs encapsulated in injectable GelMA hydrogel for spinal cord injury repair
H Wang, Q Tang, Y Lu, C Chen, Y Zhao, T Xu… - International Journal of …, 2023 - Elsevier
After spinal cord injury (SCI), local inflammatory response and fibrous scar formation
severely hinder nerve regeneration. Berberine (Ber) has a powerful regulatory effect on the …
severely hinder nerve regeneration. Berberine (Ber) has a powerful regulatory effect on the …
In Situ Cross-Linkable Hyaluronic–Ferulic Acid Conjugate Containing Bucladesine Nanoparticles Promotes Neural Regeneration after Spinal Cord Injury
F Sorouri, P Hosseini, M Sharifzadeh… - … Applied Materials & …, 2023 - ACS Publications
Dysfunctional clinical outcomes following spinal cord injury (SCI) result from glial scar
formation, leading to the inhibition of new axon growth and impaired regeneration …
formation, leading to the inhibition of new axon growth and impaired regeneration …
Human placental mesenchymal stem cell-derived exosomes in combination with hyperbaric oxygen synergistically promote recovery after spinal cord injury in rats
Spinal cord injury (SCI) is a critical medical condition during which sensorimotor function is
lost. Current treatments are still unable to effectively improve these conditions, so it is …
lost. Current treatments are still unable to effectively improve these conditions, so it is …
Regenerative effects of exosomes-derived MSCs: an overview on spinal cord injury experimental studies
G Schepici, S Silvestro, E Mazzon - Biomedicines, 2023 - mdpi.com
Spinal cord injury (SCI) is a devastating condition usually induced by the initial mechanical
insult that can lead to permanent motor and sensory deficits. At present, researchers are …
insult that can lead to permanent motor and sensory deficits. At present, researchers are …
The secondary injury cascade after spinal cord injury: an analysis of local cytokine/chemokine regulation
DJ Hellenbrand, CM Quinn, ZJ Piper… - Neural Regeneration …, 2024 - journals.lww.com
After spinal cord injury, there is an extensive infiltration of immune cells, which exacerbates
the injury and leads to further neural degeneration. Therefore, a major aim of current …
the injury and leads to further neural degeneration. Therefore, a major aim of current …
Challenges of delirium management in patients with traumatic brain injury: from pathophysiology to clinical practice
SW Roberson, MB Patel, W Dabrowski… - Current …, 2021 - benthamdirect.com
Traumatic brain injury (TBI) can initiate a very complex disease of the central nervous
system (CNS), starting with the primary pathology of the inciting trauma and subsequent …
system (CNS), starting with the primary pathology of the inciting trauma and subsequent …
Thermos-responsive hydrogel system encapsulated engineered exosomes attenuate inflammation and oxidative damage in acute spinal cord injury
Y Xiao, X Hu, P Jiang, Z Qi - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Introduction: Spinal cord injury (SCI) is a serious and disabling condition, and the
effectiveness of conventional treatment is limited, such as supportive treatment and …
effectiveness of conventional treatment is limited, such as supportive treatment and …
Biomaterial-mediated factor delivery for spinal cord injury treatment
Spinal cord injury (SCI) is an injurious process that begins with immediate physical damage
to the spinal cord and associated tissues during an acute traumatic event. However, the …
to the spinal cord and associated tissues during an acute traumatic event. However, the …