Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …

Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

CD68 is a heavily glycosylated glycoprotein that is highly expressed in macrophages and
other mononuclear phagocytes. Traditionally, CD68 is exploited as a valuable cytochemical …

IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide
and a common cause of end-stage renal disease. Evaluation of a kidney biopsy is …

Immunoglobulin G4 antibodies exhibit unusual properties with important biological
consequences. We report the structure of the human full-length IgG4 S228P anti-PD1 …

OBJECTIVE N-glycosylation is a functional posttranslational modification of
immunoglobulins (Igs). We hypothesized that specific IgG N-glycans are associated with …

Purpose: Alternative glycosylation has significant structural and functional consequences on
IgG and consequently also on cancer immunosurveillance. Because of technological …

As an important post-translation modifying process, glycosylation significantly affects the
structure and function of immunoglobulin G (IgG) molecules and is essential in many steps …

To defend against microbial invaders but also to establish symbiotic programs, plants need
to detect the presence of microbes through the perception of molecular signatures …

Immunoglobulin gamma (IgG) antibodies are key effector proteins of the immune system.
They recognize antigens with high specificity and are indispensable for immunological …