Bacterial terpenome

JD Rudolf, TA Alsup, B Xu, Z Li - Natural product reports, 2021 - pubs.rsc.org
Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Coumarins as fungal metabolites with potential medicinal properties

OM Tsivileva, OV Koftin, NV Evseeva - Antibiotics, 2022 - mdpi.com
Coumarins are a structurally varied set of 2 H-chromen-2-one compounds categorized also
as members of the benzopyrone group of secondary metabolites. Coumarin derivatives …

[图书][B] Anticancer agents from natural products

GM Cragg, DGI Kingston, DJ Newman - 2005 - taylorfrancis.com
Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

Ergot alkaloids: structure diversity, biosynthetic gene clusters and functional proof of biosynthetic genes

C Wallwey, SM Li - Natural product reports, 2011 - pubs.rsc.org
Covering: 2000 to 2010 Ergot alkaloids are toxins and important pharmaceuticals which are
produced biotechnologically on an industrial scale. They have been identified in two orders …

Bioactive compounds from marine actinomycetes

R Solanki, M Khanna, R Lal - Indian journal of microbiology, 2008 - Springer
Actinomycetes are one of the most efficient groups of secondary metabolite producers and
are very important from an industrial point of view. Among its various genera, Streptomyces …

Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

T Kuzuyama, JP Noel, SB Richard - Nature, 2005 - nature.com
The anti-oxidant naphterpin is a natural product containing a polyketide-based aromatic
core with an attached 10-carbon geranyl group derived from isoprenoid (terpene) …

Prenyltransferases as key enzymes in primary and secondary metabolism

J Winkelblech, A Fan, SM Li - Applied microbiology and biotechnology, 2015 - Springer
Attachment of isoprene units to various acceptors by prenylation plays an important role in
primary and secondary metabolism of living organisms. Protein prenylation belongs to …

The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

U Metzger, C Schall, G Zocher… - Proceedings of the …, 2009 - National Acad Sciences
Ergot alkaloids are toxins and important pharmaceuticals that are produced
biotechnologically on an industrial scale. The first committed step of ergot alkaloid …

Lyngbyatoxin biosynthesis: sequence of biosynthetic gene cluster and identification of a novel aromatic prenyltransferase

DJ Edwards, WH Gerwick - Journal of the American Chemical …, 2004 - ACS Publications
The lyngbyatoxins are potent skin irritants produced by Lyngbya majuscula and cause a
condition known as “Swimmer's Itch” off Honolulu, HI. Reported is the molecular cloning of …

Prenylation: a critical step for biomanufacturing of prenylated aromatic natural products

T An, X Feng, C Li - Journal of Agricultural and Food Chemistry, 2023 - ACS Publications
Prenylated aromatic natural products (PANPs) have received much attention due to their
biomedical benefits for human health. The prenylation of aromatic natural products (ANPs) …