Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …

The lung presents a unique challenge for iron homeostasis. The entire airway is in direct
contact with the environment and its iron particulate matter and iron-utilizing microbes …

Urinary tract infection (UTI) is the most common type of urogenital disease. UTI affects the
urethra, bladder, ureter, and kidney. A total of 13.3% of women, 2.3% of men, and 3.4% of …

Due to the developing of multi-resistant and invasive hypervirulent strains, Klebsiella
pneumoniae has become one of the most urgent bacterial pathogen threats in the last years …

In human urinary tract infections, host cells release the antimicrobial protein siderocalin
(SCN; also known as lipocalin-2, neutrophil gelatinase-associated lipocalin, or 24p3) into …

Highlights•Staphylopine is a metallophore that Staphylococcus aureus deploys to acquire
first-row transition metals.•The protein SbnI provides a link between heme uptake and …

Iron overload damages many organs. Unfortunately, therapeutic iron chelators also have
undesired toxicity and may deliver iron to microbes. Here we show that a mutant form …

Neutrophil gelatinase associated lipocalin (NGAL), was originally identified in neutrophil
granules as a heterodimer complex with gelatinase B (matrix metalloproteinase 9, MMP9) …

Aim To assess the relationship between plasma neutrophil gelatinase‐associated lipocalin
(NGAL) levels and diabetic retinopathy in patients with Type 2 diabetes. Methods In total …

Tea is thought to alleviate neurotoxicity due to the antioxidative effect of ester-type tea
catechins (ETC). Neutrophil gelatinase-associated lipocalin (NGAL) can sensitize β-amyloid …